期刊
PANCREATOLOGY
卷 18, 期 2, 页码 170-175出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.pan.2018.01.002
关键词
Agreement; BD-IPMN; EUS; Features; MRI-MRCP
资金
- EPC-Fellowship
- National Institutes of Health Research (NIHR) [PB-PG-0712-28114] Funding Source: National Institutes of Health Research (NIHR)
- National Institute for Health Research [PB-PG-0712-28114] Funding Source: researchfish
Background/objectives: To evaluate the agreement between the imaging modalities MRI-MRCP and EUS in cystic lesions of the pancreas which were thought to be a BD-IPMN. Methods: Multicenter retrospective study included all patients between 2010 and 2015 with a suspected BD-IPMN who underwent an EUS and MRI-MRCP within 6 months or less of each other. Location, number, size, worrisome features and high-risk stigmata were evaluated. Interobserver agreement was evaluated by Kappa score. Results: 173 patients were included (97 UHSC, 76 UCLH-RFH), mean age 65 (range 25-87 years), 66 males. When comparing both modalities there was good agreement for the location of the cyst. The median lesion size was larger by MRI-MRCP than EUS although it was not significant. With regards to worrisome features, there was moderate agreement for main PD of 5-9mm and abrupt change (k = 0.45 and 0.52). Fair agreement was seen for the cyst wall thickening (k = 0.25). No agreement was seen between the presence of non-enhanced mural nodules or lymphadenopathy (k < 0). With regards to high-risk stigmata, poor agreement was obtained for the detection of an enhanced solid component (k = 0.12). No agreement was observed for main PD > 10mm(k < 0). Conclusions: In this multicentre study of patients with a BD-IPMN under active surveillance, most disagreement between these modalities was seen in the proximal pancreas. There was generally only minimal concordance between the imaging findings of EUS and MRI-MRCP for the detection of high-risk stigmata and worrisome features. (C) 2018 IAP and EPC. Published by Elsevier B.V. All rights reserved.
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