期刊
ORGANIC LETTERS
卷 20, 期 14, 页码 4285-4289出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b01707
关键词
-
资金
- National Natural Science Foundation of China [21761132014]
- Fundamental Research Funds for the Central Universities of China [2016YXZD033]
- Hubei Key Laboratory of Material Chemistry and Service Failure [2017MCF01K]
A three-component reaction of indoles, alpha-bromoacetaldehyde acetals, and ketones was developed by using bismuth(III) triflate as the catalyst to realize a straightforward approach for synthesizing carbazole derivatives. The reaction was established mechanistically through the autotandem catalysis of Bi(OTf)(3) in the following two steps: (i) Friedel-Crafts-type alkylation of indole with alpha-bromoacetaldehyde acetal, which produced a tryptaldehyde-type intermediate and (ii) [4 + 2] annulation of this intermediate with the ketone component.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据