期刊
ORGANIC LETTERS
卷 20, 期 2, 页码 349-352出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.7b03587
关键词
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资金
- Natural Science Foundation of Fujian Province [2016J01064]
- Recruitment Program of Global Experts (1000 Talents Plan)
- Program of Innovative Research Team of Huaqiao University [Z14 X 0047]
- Graduate Innovation Fund of Huaqiao University
PhotbrOdok-catalyzed decarboxylative alkylation of silyl enol ethers has been developed. Diverse functionalized aryl alkyl ketones were afforded in modest to good yields using N-(acylory) phthalimide as an easy access alkyl radical source under mild and operationally simple conditions. The excellent performance of drug molecules such as fenbufen and indomethacin and naturally occurring carboxylic acids such as stearic acid and dehydrocholic acid-further demonstrated the practicability of the reaction.
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