Triflates-Triggered Intermolecular Cyclization of Carbodiimides Leading to 2-Aminoquinazolinone and 2,4-Diaminoquinazoline Derivatives

A triflate-triggered intermolecular cyclization of carbodiimides to provide 2-amino-4-imino-quinazolines, which could be easily transformed to 2-aminoquinazolinones and 2,4-diaminoquinazolines in high yield, has been reported. A variety of functional groups are tolerated in the 2-amino-4-iminoquinazoline scaffolds.