期刊
ORGANIC LETTERS
卷 20, 期 5, 页码 1359-1362出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b00127
关键词
-
资金
- University Grants Commission, New Delhi
- SERB, Government of India [ECR/2016/000134]
The potential of 2-aminoquinazolin-4(3H)-one as an organocatalyst for the activation of aldehydes via noncovalent interaction for the synthesis of tertiary amines using formic acid as a reducing agent is reported for the first time. The developed protocol demonstrated a dilated substrate scope for aromatic and aliphatic amines with aromatic and aliphatic aldehydes. Furthermore, the current method was also fruitful for the derivatization of ciprofloxacin and its derivative in good to excellent yields.
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