期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 16, 期 12, 页码 2143-2149出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7ob03109b
关键词
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A sequential one-pot approach towards N,N-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines is reported. This strategy provides straightforward and efficient access to diverse guanidines in yields up to 81% through previously unprecedented N-phthaloylguanidines. This protocol also features wide substrate scope and mild conditions.
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