PhI(OAc)2-mediated dearomative C-N coupling: facile construction of the spiro[indoline-3,2′-pyrrolidine] skeleton

A facile construction of the spiro[indole-3,2-pyrrolidine] skeleton, through diacetoxyiodobenzene (PIDA) mediated C-N bond-forming dearomatization of C3 sulfonamide linked indole derivatives, has been developed. A variety of spiro-indolepyrrolidines were obtained in moderate to excellent yields under mild conditions.