相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Fingolimod May Support Neuroprotection via Blockade of Astrocyte Nitric Oxide
Emanuela Colombo et al.
ANNALS OF NEUROLOGY (2014)
Fingolimod increases brain-derived neurotrophic factor levels and ameliorates amyloid β-induced memory impairment
Kazuya Fukumoto et al.
BEHAVIOURAL BRAIN RESEARCH (2014)
Second generation S1P pathway modulators: Research strategies and clinical developments
Marc Bigaud et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2014)
FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease
Alba Di Pardo et al.
HUMAN MOLECULAR GENETICS (2014)
Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease
Han-Yun Hsiao et al.
HUMAN MOLECULAR GENETICS (2014)
Neurotrophin receptor p75NTR mediates Huntington's disease-associated synaptic and memory dysfunction
Veronica Brito et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Prostaglandin E2 EP1 Receptor Antagonist Improves Motor Deficits and Rescues Memory Decline in R6/1 Mouse Model of Huntington's Disease
Marta Anglada-Huguet et al.
MOLECULAR NEUROBIOLOGY (2014)
Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory
Nitai C. Hait et al.
NATURE NEUROSCIENCE (2014)
Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington's Disease
Joshua L. Plotkin et al.
NEURON (2014)
INTERLEUKIN-1β ENHANCES NEURONAL VULNERABILITY TO PRONGF-MEDIATED APOPTOSIS BY INCREASING SURFACE EXPRESSION OF P75NTR AND SORTILLIN
S. Choi et al.
NEUROSCIENCE (2014)
Pathway specific modulation of S1P1 receptor signalling in rat and human astrocytes
Luke M. Healy et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a Huntington's disease mouse model
Albert Giralt et al.
HIPPOCAMPUS (2013)
A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease
Han-Yun Hsiao et al.
HUMAN MOLECULAR GENETICS (2013)
FTY720 (Fingolimod) Attenuates Beta-amyloid Peptide (Aβ42)-Induced Impairment of Spatial Learning and Memory in Rats
Masoumeh Asle-Rousta et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2013)
Fingolimod phosphate promotes the neuroprotective effects of microglia
Hiromi Noda et al.
JOURNAL OF NEUROIMMUNOLOGY (2013)
Dendritic Spine Instability Leads to Progressive Neocortical Spine Loss in a Mouse Model of Huntington's Disease
Reena Prity Murmu et al.
JOURNAL OF NEUROSCIENCE (2013)
A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington's Disease
Danielle A. Simmons et al.
JOURNAL OF NEUROSCIENCE (2013)
Sustained, neuron-specific IKK/NF-κB activation generates a selective neuroinflammatory response promoting local neurodegeneration with aging
Ayesha Maqbool et al.
MOLECULAR NEURODEGENERATION (2013)
Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models
Sonia Marco et al.
NATURE MEDICINE (2013)
A small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model
Juliet K. Knowles et al.
NEUROBIOLOGY OF AGING (2013)
Imbalance of p75NTR/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies
V. Brito et al.
CELL DEATH & DISEASE (2013)
A deconvolution method to improve automated 3D-analysis of dendritic spines: application to a mouse model of Huntington's disease
Nicolas Heck et al.
BRAIN STRUCTURE & FUNCTION (2012)
Oral fingolimod rescues the functional deficits of synapses in experimental autoimmune encephalomyelitis
S. Rossi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease
Ana Ricobaraza et al.
HIPPOCAMPUS (2012)
Long-term memory deficits in Huntingtons disease are associated with reduced CBP histone acetylase activity
A. Giralt et al.
HUMAN MOLECULAR GENETICS (2012)
The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflammatory and apoptotic responses in rats
Chuang Wang et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2012)
TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
Karim Belarbi et al.
JOURNAL OF NEUROINFLAMMATION (2012)
Brain-Derived Neurotrophic Factor-Dependent Synaptic Plasticity Is Suppressed by Interleukin-1β via p38 Mitogen-Activated Protein Kinase
Liqi Tong et al.
JOURNAL OF NEUROSCIENCE (2012)
Aging and infection reduce expression of specific brain-derived neurotrophic factor mRNAs in hippocampus
Timothy R. Chapman et al.
NEUROBIOLOGY OF AGING (2012)
Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome
Ruben Deogracias et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Immune modulation of learning, memory, neural plasticity and neurogenesis
Raz Yirmiya et al.
BRAIN BEHAVIOR AND IMMUNITY (2011)
Dynamics of Retrieval Strategies for Remote Memories
Inbal Goshen et al.
CELL (2011)
Cognitive Impairment in Huntington Disease: Diagnosis and Treatment
Jane S. Paulsen
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2011)
Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease
Albert Giralt et al.
HUMAN MOLECULAR GENETICS (2011)
Shape analysis of subcortical nuclei in Huntington's disease, global versus local atrophy - Results from the TRACK-HD study
S. J. A. van den Bogaard et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2011)
Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction
Albert Giralt et al.
MOLECULAR NEURODEGENERATION (2011)
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
Ji Woong Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mechanisms Underlying Inflammation in Neurodegeneration
Christopher K. Glass et al.
CELL (2010)
BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease
A. Giralt et al.
GENE THERAPY (2010)
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects
Mathilde Faideau et al.
HUMAN MOLECULAR GENETICS (2010)
Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice
Jennifer Bradford et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Synaptic Correlates of Increased Cognitive Vulnerability with Aging: Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1
Timothy R. Chapman et al.
JOURNAL OF NEUROSCIENCE (2010)
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
Volker Brinkmann et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Inflammatory cytokines IL-1 beta and TNF-alpha regulate p75(NTR) expression in CNS neurons and astrocytes by distinct cell-type-specific signalling mechanisms
Soyoung Choi et al.
ASN NEURO (2009)
NOS2 Gene Deficiency Protects from Sepsis-Induced Long-Term Cognitive Deficits
Marc Weberpals et al.
JOURNAL OF NEUROSCIENCE (2009)
Brain-derived neurotrophic factor in neurodegenerative diseases
Chiara Zuccato et al.
NATURE REVIEWS NEUROLOGY (2009)
BRAIN-DERIVED NEUROTROPHIC FACTOR MODULATES THE SEVERITY OF COGNITIVE ALTERATIONS INDUCED BY MUTANT huntingtin: INVOLVEMENT OF PHOSPHOLIPASECγ ACTIVITY AND GLUTAMATE RECEPTOR EXPRESSION
A. Giralt et al.
NEUROSCIENCE (2009)
Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms
Jennifer Bradford et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
Maria Bjorkqvist et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Detection of Huntington's disease decades before diagnosis: the Predict-HD study
J. S. Paulsen et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2008)
Gene-environment interactions modulating cognitive function and molecular correlates of synaptic plasticity in Huntington's disease transgenic mice
Jess Nithianantharajah et al.
NEUROBIOLOGY OF DISEASE (2008)
Disruption of striatal glutamatergic transmission induced by mutant huntingtin involves remodeling of both postsynaptic density and NMDA receptor signaling
Jess F. Torres-Peraza et al.
NEUROBIOLOGY OF DISEASE (2008)
Functional consequences of S1P receptor modulation in rat oligodendroglial lineage cells
C. G. Jung et al.
GLIA (2007)
Connecting TNF-α signaling pathways to iNOS expression in a mouse model of Alzheimer's disease:: Relevance for the Behavioral and synaptic deficits induced by amyloid β protein
Rodrigo Medeiros et al.
JOURNAL OF NEUROSCIENCE (2007)
Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease
Anton Alvarez et al.
NEUROBIOLOGY OF AGING (2007)
The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons
M Zagrebelsky et al.
JOURNAL OF NEUROSCIENCE (2005)
Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice
EC Stack et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2005)
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
NH Woo et al.
NATURE NEUROSCIENCE (2005)
Brain-derived neurotrophic factor modulates dopaminergic deficits in a transgenic mouse model of Huntington's disease
JR Pineda et al.
JOURNAL OF NEUROCHEMISTRY (2005)
The secreted brain-derived neurotrophic factor precursor pro-BDNF binds to TrkB and p75NTR but not to TrkA or TrkC
B Fayard et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2005)
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease
JM Canals et al.
JOURNAL OF NEUROSCIENCE (2004)
PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate
SC Pierre et al.
EMBO JOURNAL (2004)
Dendritic spine pathology and deficits in experience-dependent dendritic plasticity in R6/1 Huntington's disease transgenic mice
TL Spires et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Evidence for more widespread cerebral pathology in early HD - An MRI-based morphometric analysis
HD Rosas et al.
NEUROLOGY (2003)
Targeting the CREB pathway for memory enhancers
T Tully et al.
NATURE REVIEWS DRUG DISCOVERY (2003)
Increased p75NTR expression in hippocampal neurons containing hyperphosphorylated tin Alzheimer patients
XY Hu et al.
EXPERIMENTAL NEUROLOGY (2002)
Dendritic spine pathology: Cause or consequence of neurological disorders?
JC Fiala et al.
BRAIN RESEARCH REVIEWS (2002)
Regional and progressive thinning of the cortical ribbon in Huntington's disease
HD Rosas et al.
NEUROLOGY (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Regulation of cell survival by secreted proneurotrophins
R Lee et al.
SCIENCE (2001)
Bone morphogenetic protein-2, but not bone morphogenetic protein-7, promotes dendritic growth and calbindin phenotype in cultured rat striatal neurons
E Gratacos et al.
NEUROSCIENCE (2001)
Tumor necrosis factor has positive and negative self regulatory feed back cycles centered around cAMP
RE Kast
INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY (2000)
Regulation of dendritic spine morphology by the Rho family of small GTPases: Antagonistic roles of Rac and Rho
A Tashiro et al.
CEREBRAL CORTEX (2000)
分享论文
