4.4 Article

Safety and efficacy following 10-years of overnight orthokeratology for myopia control

期刊

OPHTHALMIC AND PHYSIOLOGICAL OPTICS
卷 38, 期 3, 页码 281-289

出版社

WILEY
DOI: 10.1111/opo.12460

关键词

long-term; myopia control; myopia progression; orthokeratology; schoolchildren; soft contact lens

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PurposeTo compare rates of myopia progression and adverse events between orthokeratology (OK) and soft contact lens (SCL) wearers over a 10-year period in schoolchildren. MethodsMedical records of consecutive patients (16years of age at baseline) who started OK for myopia correction and continued the treatment for 10years were retrospectively reviewed. For the control group, patients who started using soft contact lenses (SCLs) for myopia correction and continued to use them for 10years were also reviewed. Clinical data, including sex, age, manifest refraction, visual acuity, prescription lens power, and adverse events during the 10-year period, were recorded. Estimated myopia progression was calculated as the sum of changes in prescription lens power during 10years' and residual refractive errors at the 10-year visit,' and was compared between groups. We also compared the incidence of adverse events between groups over the 10-year study period. ResultsA total of 104 eyes of 53 patients who underwent OK treatment and 78 eyes of 39 patients who wore SCLs fulfilled the criteria. The estimated myopia progression over the 10-year period found in the OK and SCL groups were -1.260.98 and -1.79 +/- 1.24days, respectively; this difference was statistically significant (p=0.001). Additionally, lower myopia progression was found in the OK in comparison to the SCL group at all baseline ages (p=0.003 to p=0.049) except at 16years old (p=0.41). No significant difference was found in the number of adverse events found between the OK (119) and SCL (103) groups (p=0.72). ConclusionsThe results of this study supports the long-term efficacy and safety of OK lens wear in reducing myopia progression in schoolchildren.

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