期刊
PARASITE
卷 20, 期 -, 页码 -出版社
EDP SCIENCES S A
DOI: 10.1051/parasite/2013024
关键词
Trypanosomiasis; Trypanosoma vivax; Zambia; Ghana
类别
资金
- program of Funding Research Center for Emerging and Re-emerging Infectious Disease from Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT)
- Grants-in-Aid for Scientific Research [25850195] Funding Source: KAKEN
Understanding the evolutionary relationships of Trypanosoma (Duttonella) vivax genotypes between West Africa and Southern Africa can provide information on the epidemiology and control of trypanosomosis. Cattle blood samples from Zambia and Ghana were screened for T. vivax infection using specie-specific PCR and sequencing analysis. Substantial polymorphism was obtained from phylogenetic analysis of sequences of cathepsin L-like catalytic domains. T. vivax from Ghana clustered together with West African and South American sequences, while T. vivax from Zambia formed one distinct clade and clustered with East African and Southern African sequences. This study suggests existence of distinct genetic diversity between T. vivax genotypes from West Africa and Zambia as per their geographical origins.
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