期刊
NEUROSURGERY CLINICS OF NORTH AMERICA
卷 29, 期 2, 页码 195-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nec.2017.12.001
关键词
Intracranial pressure; Intracranial hypertension; Acute brain injury; Cerebral perfusion pressure; Cerebral oxygenation; Brain hypoxia; Multimodal monitoring; Traumatic brain injury
Monitoring intracranial pressure in comatose patients with severe traumatic brain injury (TBI) is considered necessary by most experts. Acute intracranial hypertension (IHT), when severe and sustained, is a life-threatening complication that demands emergency treatment. Yet, secondary anoxic-ischemic injury after brain trauma can occur in the absence of IHT. In such cases, adding other monitoring modalities can alert clinicians when the patient is in a state of energy failure. This article reviews the mechanisms, diagnosis, and treatment of IHT and brain hypoxia after TBI, emphasizing the need to develop a physiologically integrative approach to the management of these complex situations.
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