期刊
3RD INTERNATIONAL CONFERENCE ON TISSUE ENGINEERING (ICTE2013)
卷 59, 期 -, 页码 298-306出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.proeng.2013.05.125
关键词
Computacional tecnologies; Topological optimisation; Tissue engineering; Scaffolds
Advanced additive manufacturing technologies, namely Biomanufacturing, are being used to fabricate scaffolds with controlled architecture for tissue engineering applications. These technologies combined with computer-aided design (CAD) enable to produce three-dimensional structures layer-by-layer in a multitude of materials. Actual prediction of the effective mechanical properties of scaffolds produced by Biomanufacturing, is very important for tissue engineering applications. A novel computer based technique for scaffold design is topological optimisation. Topological optimisation is a form of shape optimisation, usually referred to as layout optimisation. The goal of topological optimisation is to find the best use of material for a body that is subjected to either a single load or a multiple load distribution. This paper proposes a topological optimisation scheme in order to obtain the ideal topological architectures of scaffolds, maximising its mechanical behaviour. (C) 2013 The Authors. Published by Elsevier Ltd.
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