期刊
NEURON
卷 98, 期 5, 页码 878-879出版社
CELL PRESS
DOI: 10.1016/j.neuron.2018.05.032
关键词
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资金
- National Research Foundation of Korea (NRF) - Ministry of Science, ICT,& Future Planning [2016R1A2B3015167, 2017R1A2B3011098, 2017M3C7A1023471]
- Institute for Basic Science [IBS-R001-D1]
- National Research Foundation of Korea [2016R1A2B3015167, 2017M3C7A1023471, 2017R1A2B3011098] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
The N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine has been found to have rapid and long-lasting antidepressive effects. Two elegant studies from Hailan Hu's laboratory (Cui et al., 2018; Yang et al., 2018) showed that ketamine blocks burst firing of neurons in the lateral habenula (LHb), rapidly relieving symptoms of depression.
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