期刊
DEVELOPMENTAL SCIENCE
卷 16, 期 5, 页码 641-652出版社
WILEY
DOI: 10.1111/desc.12096
关键词
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资金
- NIBIB NIH HHS [R01 EB006266, EB006266] Funding Source: Medline
- NICHD NIH HHS [HD055689, R01 HD055689] Funding Source: Medline
- NIDA NIH HHS [DA022807, DA014129, R01 DA014129, R01 DA022807] Funding Source: Medline
- NINDS NIH HHS [P30 NS045839, NS045839] Funding Source: Medline
Childhood socioeconomic status (SES) predicts executive function performance and measures of prefrontal cortical function, but little is known about its anatomical correlates. Structural MRI and demographic data from a sample of 283 healthy children from the NIH MRI Study of Normal Brain Development were used to investigate the relationship between SES and prefrontal cortical thickness. Specifically, we assessed the association between two principal measures of childhood SES, family income and parental education, and gray matter thickness in specific subregions of prefrontal cortex and on the asymmetry of these areas. After correcting for multiple comparisons and controlling for potentially confounding variables, parental education significantly predicted cortical thickness in the right anterior cingulate gyrus and left superior frontal gyrus. These results suggest that brain structure in frontal regions may provide a meaningful link between SES and cognitive function among healthy, typically developing children.
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