4.7 Review

Autophagy as a promoter of longevity: insights from model organisms

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Physiology

Mitochondrial dysfunction and pulmonary hypertension: cause, effect, or both

Jeffrey D. Marshall et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2018)

Article Biochemistry & Molecular Biology

Lipid metabolism and lipophagy in cancer

Meenu Maan et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Cell Biology

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

Thomas G. McWilliams et al.

CELL METABOLISM (2018)

Review Cell Biology

The coming of age of chaperone-mediated autophagy

Susmita Kaushik et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Review Cell Biology

Mechanism and medical implications of mammalian autophagy

Ivan Dikic et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Review Multidisciplinary Sciences

Spermidine in health and disease

Frank Madeo et al.

SCIENCE (2018)

Review Biochemistry & Molecular Biology

Role of gut microbiota in aging-related health decline: insights from invertebrate models

Rebecca I. Clark et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2018)

Article Biochemistry & Molecular Biology

VCP/p97 cooperates with YOD1, UBXD1 and PLAA to drive clearance of ruptured lysosomes by autophagy

Chrisovalantis Papadopoulos et al.

EMBO JOURNAL (2017)

Article Biochemistry & Molecular Biology

Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans

Konstantinos Palikaras et al.

JOURNAL OF LIPID RESEARCH (2017)

Article Cell Biology

Tricellular junctions regulate intestinal stem cell behaviour to maintain homeostasis

Martin Resnik-Docampo et al.

NATURE CELL BIOLOGY (2017)

Article Geriatrics & Gerontology

Activation-Induced Autophagy Is Preserved in CD4+T-Cells in Familial Longevity

Yotam Raz et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2017)

Article Multidisciplinary Sciences

Autophagy maintains the metabolism and function of young and old stem cells

Theodore T. Ho et al.

NATURE (2017)

Article Multidisciplinary Sciences

Hypothalamic stem cells control ageing speed partly through exosomal miRNAs

Yalin Zhang et al.

NATURE (2017)

Article Multidisciplinary Sciences

Polyglutamine tracts regulate beclin 1-dependent autophagy

Avraham Ashkenazi et al.

NATURE (2017)

Article Cell Biology

Mitochondrial quality control in amyotrophic lateral sclerosis: towards a common pathway?

Bilal Khalil et al.

NEURAL REGENERATION RESEARCH (2017)

Review Pharmacology & Pharmacy

Mitophagy and age-related pathologies: Development of new therapeutics by targeting mitochondrial turnover

Konstantinos Palikaras et al.

PHARMACOLOGY & THERAPEUTICS (2017)

Article Multidisciplinary Sciences

Hormetic heat stress and HSF-1 induce autophagy to improve survival and proteostasis in C. elegans

Caroline Kumsta et al.

NATURE COMMUNICATIONS (2017)

Review Neurosciences

Neuronal Mitophagy in Neurodegenerative Diseases

Marta Martinez-Vicente

FRONTIERS IN MOLECULAR NEUROSCIENCE (2017)

Article Biochemistry & Molecular Biology

Breaking fat: The regulation and mechanisms of lipophagy

Ryan J. Schulze et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2017)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth, Metabolism, and Disease

Robert A. Saxton et al.

Article Biochemistry & Molecular Biology

Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles

E. Fiacco et al.

CELL DEATH AND DIFFERENTIATION (2016)

Review Cell Biology

The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging

Brian K. Kennedy et al.

CELL METABOLISM (2016)

Review Biochemistry & Molecular Biology

Resveratrol and Lifespan in Model Organisms

Kathrin Pallauf et al.

CURRENT MEDICINAL CHEMISTRY (2016)

Review Urology & Nephrology

Autophagy in kidney disease and aging: lessons from rodent models

Olivia Lenoir et al.

KIDNEY INTERNATIONAL (2016)

Review Biochemistry & Molecular Biology

The Mitochondrial Basis of Aging

Nuo Sun et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Autophagy maintains stemness by preventing senescence

Laura Garcia-Prat et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Urolithin A induces mitophagy and prolongs lifespan in C-elegans and increases muscle function in rodents

Dongryeol Ryu et al.

NATURE MEDICINE (2016)

Review Cell Biology

Ubiquitin-Dependent And Independent Signals In Selective Autophagy

Aliaksandr Khaminets et al.

TRENDS IN CELL BIOLOGY (2016)

Review Biochemistry & Molecular Biology

Autophagy and Immune Senescence

Hanlin Zhang et al.

TRENDS IN MOLECULAR MEDICINE (2016)

Review Cell Biology

Transcriptional and epigenetic regulation of autophagy in aging

Louis R. Lapierre et al.

AUTOPHAGY (2015)

Article Biochemistry & Molecular Biology

Iron-Starvation-Induced Mitophagy Mediates Lifespan Extension upon Mitochondrial Stress in C. elegans

Alfonso Schiavi et al.

CURRENT BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Autophagy Enhances Intestinal Epithelial Tight Junction Barrier Function by Targeting Claudin-2 Protein Degradation

Prashant K. Nighot et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Measuring In Vivo Mitophagy

Nuo Sun et al.

MOLECULAR CELL (2015)

Article Neurosciences

Mutations in LRRK2 potentiate age-related impairment of autophagic flux

Shamol Saha et al.

MOLECULAR NEURODEGENERATION (2015)

Article Multidisciplinary Sciences

Coordination of mitophagy and mitochondrial biogenesis during ageing in C-elegans

Konstantinos Palikaras et al.

NATURE (2015)

Article Neurosciences

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

Axel Freischmidt et al.

NATURE NEUROSCIENCE (2015)

Article Multidisciplinary Sciences

Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans

Andrew Folick et al.

SCIENCE (2015)

Review Biochemistry & Molecular Biology

You Are What You Host: Microbiome Modulation of the Aging Process

Caroline Heintz et al.

Review Cell Biology

The machinery of macroautophagy

Yuchen Feng et al.

CELL RESEARCH (2014)

Article Gastroenterology & Hepatology

Crohn's Disease: Loss of Tolerance or a Disorder of Autophagy?

Marianne R. Spalinger et al.

DIGESTIVE DISEASES (2014)

Article Biochemistry & Molecular Biology

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

Ann H. Tang et al.

EMBO JOURNAL (2014)

Review Geriatrics & Gerontology

The paradox of mitochondrial dysfunction and extended longevity

Erin Munkacsy et al.

EXPERIMENTAL GERONTOLOGY (2014)

Article Geriatrics & Gerontology

Downregulation of E3 Ubiquitin Ligases and Mitophagy-Related Genes in Skeletal Muscle of Physically Inactive, Frail Older Women: A Cross-Sectional Comparison

Micah J. Drummond et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)

Article Oncology

Autophagy Is Required for Glucose Homeostasis and Lung Tumor Maintenance

Gizem Karsli-Uzunbas et al.

CANCER DISCOVERY (2014)

Article Cell Biology

AMPK Modulates Tissue and Organismal Aging in a Non-Cell-Autonomous Manner

Matthew Ulgherait et al.

CELL REPORTS (2014)

Article Genetics & Heredity

Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

Christoph Ruckenstuhl et al.

PLOS GENETICS (2014)

Review Cell Biology

Organ-specific mediation of lifespan extension: More than a gut feeling?

Michael Rera et al.

AGEING RESEARCH REVIEWS (2013)

Review Cell Biology

The influence of skeletal muscle on systemic aging and lifespan

Fabio Demontis et al.

AGING CELL (2013)

Review Biochemistry & Molecular Biology

The Hallmarks of Aging

Carlos Lopez-Otin et al.

Review Biochemistry & Molecular Biology

The pathways of mitophagy for quality control and clearance of mitochondria

G. Ashrafi et al.

CELL DEATH AND DIFFERENTIATION (2013)

Review Cell Biology

Reproduction, Fat Metabolism, and Life Span: What Is the Connection?

Malene Hansen et al.

CELL METABOLISM (2013)

Article Biochemistry & Molecular Biology

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

Ikuko Maejima et al.

EMBO JOURNAL (2013)

Article Cell Biology

ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy

Eyleen J. O'Rourke et al.

GENES & DEVELOPMENT (2013)

Article Multidisciplinary Sciences

Identification of a candidate therapeutic autophagy-inducing peptide

Sanae Shoji-Kawata et al.

NATURE (2013)

Article Cell Biology

MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability

Eyleen J. O'Rourke et al.

NATURE CELL BIOLOGY (2013)

Article Multidisciplinary Sciences

Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan

Anil Rana et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Genetics & Heredity

Mutation in TECPR2 Reveals a Role for Autophagy in Hereditary Spastic Paraparesis

Danit Oz-Levi et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Article Genetics & Heredity

Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA

Tobias B. Haack et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Editorial Material Cell Biology

Autophagosome assembly and cargo capture in the distal axon

Sandra Maday et al.

AUTOPHAGY (2012)

Review Cardiac & Cardiovascular Systems

Contribution of Impaired Mitochondrial Autophagy to Cardiac Aging Mechanisms and Therapeutic Opportunities

Debapriya Dutta et al.

CIRCULATION RESEARCH (2012)

Article Biochemistry & Molecular Biology

Loss of autophagy in hypothalamic POMC neurons impairs lipolysis

Susmita Kaushik et al.

EMBO REPORTS (2012)

Article Multidisciplinary Sciences

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

Adam L. Hughes et al.

NATURE (2012)

Article Multidisciplinary Sciences

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila

Michael Rera et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Cell Biology

Selective autophagy mediated by autophagic adapter proteins

Terje Johansen et al.

AUTOPHAGY (2011)

Article Biochemistry & Molecular Biology

Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans

Louis R. Lapierre et al.

CURRENT BIOLOGY (2011)

Review Cell Biology

Mechanisms of mitophagy

Richard J. Youle et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)

Article Multidisciplinary Sciences

TFEB Links Autophagy to Lysosomal Biogenesis

Carmine Settembre et al.

SCIENCE (2011)

Review Multidisciplinary Sciences

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

Douglas R. Green et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

Fabio Demontis et al.

Article Geriatrics & Gerontology

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

Stephanie Eva Wohlgemuth et al.

EXPERIMENTAL GERONTOLOGY (2010)

Article Cell Biology

α-Synuclein impairs macroautophagy: implications for Parkinson's disease

Ashley R. Winslow et al.

JOURNAL OF CELL BIOLOGY (2010)

Review Multidisciplinary Sciences

Neural mechanisms of ageing and cognitive decline

Nicholas A. Bishop et al.

NATURE (2010)

Review Multidisciplinary Sciences

The genetics of ageing

Cynthia J. Kenyon

NATURE (2010)

Article Multidisciplinary Sciences

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

Marta M. Lipinski et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Biochemistry & Molecular Biology

Insulin/IGF-like signalling, the central nervous system and aging

Susan Broughton et al.

BIOCHEMICAL JOURNAL (2009)

Article Multidisciplinary Sciences

Autophagy regulates lipid metabolism

Rajat Singh et al.

NATURE (2009)

Article Cell Biology

Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg et al.

NATURE CELL BIOLOGY (2009)

Review Biochemistry & Molecular Biology

Autophagy in the pathogenesis of disease

Beth Levine et al.

Article Medicine, General & Internal

Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

M. D. W. Piper et al.

JOURNAL OF INTERNAL MEDICINE (2008)

Article Geriatrics & Gerontology

Effect of aging and anti-aging caloric restriction on the endocrine regulation of rat liver autophagy

Alessio Donati et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)

Article Genetics & Heredity

A role for autophagy in the extension of lifespan by dietary restriction in C-elegans

Malene Hansen et al.

PLOS GENETICS (2008)

Article Multidisciplinary Sciences

Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans

Meng C. Wang et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

The C-elegans TGF-β dauer pathway regulates longevity via insulin signaling

Wendy M. Shaw et al.

CURRENT BIOLOGY (2007)

Review Cell Biology

Autophagy and human disease

Ju Huang et al.

CELL CYCLE (2007)

Article Cell Biology

Autophagy regulates ageing in C-elegans

Enter S. Hars et al.

AUTOPHAGY (2007)

Article Biochemistry & Molecular Biology

Rapamycin alleviates toxicity of different aggregate-prone proteins

Z Berger et al.

HUMAN MOLECULAR GENETICS (2006)

Article Multidisciplinary Sciences

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

SJ Broughton et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

α-synuclein is degraded by both autophagy and the proteasome

JL Webb et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Geriatrics & Gerontology

Ageing-related changes in the in vivo function of rat liver macroautophagy and proteolysis

A Del Roso et al.

EXPERIMENTAL GERONTOLOGY (2003)

Article Multidisciplinary Sciences

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

JC Greene et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Genetics & Heredity

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone

N Laurin et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2002)

Article Biochemistry & Molecular Biology

Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

B Ravikumar et al.

HUMAN MOLECULAR GENETICS (2002)

Article Geriatrics & Gerontology

Age-related changes in the autophagic proteolysis of rat isolated liver cells: Effects of antiaging dietary restrictions

A Donati et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)

Article Geriatrics & Gerontology

Age-related changes in the regulation of autophagic proteolysis in rat isolated hepatocytes

A Donati et al.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2001)

Article Biochemistry & Molecular Biology

Age-related decline in chaperone-mediated autophagy

AM Cuervo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)