期刊
NATURE REVIEWS CLINICAL ONCOLOGY
卷 15, 期 6, 页码 341-342出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41571-018-0016-0
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According to the paradigm of precision medicine, the administration of agents targeting the molecular alteration detected in a particular patient's tumour reduces uncertainty in the clinical management of that patient. We describe how approaches to precision medicine can lead, paradoxically, to increased levels of uncertainty. We offer recommendations for how physicians can better navigate new uncertainties in precision medicine.
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