4.8 Article

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

Jacqueline MacArthur et al.

NUCLEIC ACIDS RESEARCH (2017)

Review Public, Environmental & Occupational Health

Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

Stephen Burgess et al.

EPIDEMIOLOGY (2017)

Article Public, Environmental & Occupational Health

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

Fernando Pires Hartwig et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

Thomas R. Webb et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

Article Mathematical & Computational Biology

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

Jack Bowden et al.

STATISTICS IN MEDICINE (2017)

Letter Public, Environmental & Occupational Health

Why internal weights should be avoided (not only) in MR-Egger regression Response

Jack Bowden et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2016)

Article Genetics & Heredity

Detection and interpretation of shared genetic influences on 42 human traits

Joseph K. Pickrell et al.

NATURE GENETICS (2016)

Editorial Material Genetics & Heredity

Genetic pleiotropy in complex traits and diseases: implications for genomic medicine

Jacob Gratten et al.

GENOME MEDICINE (2016)

Article Public, Environmental & Occupational Health

Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects

Stephen Burgess et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2015)

Review Genetics & Heredity

Mendelian Randomization: New Applications in the Coming Age of Hypothesis-Free Causality

David M. Evans et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 16 (2015)

Article Public, Environmental & Occupational Health

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

Stephen Burgess et al.

EUROPEAN JOURNAL OF EPIDEMIOLOGY (2015)

Article Public, Environmental & Occupational Health

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

Jack Bowden et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2015)

Article Multidisciplinary Sciences

A global reference for human genetic variation

David M. Altshuler et al.

NATURE (2015)

Article Genetics & Heredity

An atlas of genetic correlations across human diseases and traits

Brendan Bulik-Sullivan et al.

NATURE GENETICS (2015)

Article Mathematical & Computational Biology

Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome

Fabiola M. Del Greco et al.

STATISTICS IN MEDICINE (2015)

Review Genetics & Heredity

Mendelian randomisation applied to drug development in cardiovascular disease: a review

Lauren E. Mokry et al.

JOURNAL OF MEDICAL GENETICS (2015)

Article Genetics & Heredity

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

Michael V. Holmes et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2014)

Article Biochemical Research Methods

Fast and accurate imputation of summary statistics enhances evidence of functional enrichment

Bogdan Pasaniuc et al.

BIOINFORMATICS (2014)

Article Genetics & Heredity

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

Stephen Burgess et al.

GENETIC EPIDEMIOLOGY (2013)

Review Biotechnology & Applied Microbiology

Validating therapeutic targets through human genetics

Robert M. Plenge et al.

NATURE REVIEWS DRUG DISCOVERY (2013)

Review Genetics & Heredity

Genetic insights into common pathways and complex relationships among immune-mediated diseases

Miles Parkes et al.

NATURE REVIEWS GENETICS (2013)

Review Genetics & Heredity

Pleiotropy in complex traits: challenges and strategies

Nadia Solovieff et al.

NATURE REVIEWS GENETICS (2013)

Article Genetics & Heredity

Abundant Pleiotropy in Human Complex Diseases and Traits

Shanya Sivakumaran et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Review Cardiac & Cardiovascular Systems

Biomarkers of cardiovascular disease - Molecular basis and practical considerations

Ramachandran S. Vasan

CIRCULATION (2006)

Article Medicine, General & Internal

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

JC Cohen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Public, Environmental & Occupational Health

'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease?

GD Smith et al.

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2003)