4.8 Article

Signatures of negative selection in the genetic architecture of human complex traits

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Multidisciplinary Sciences

Rare and low-frequency coding variants alter human adult height

Eirini Marouli et al.

NATURE (2017)

Article Genetics & Heredity

Reevaluation of SNP heritability in complex human traits

Doug Speed et al.

NATURE GENETICS (2017)

Review Genetics & Heredity

10 Years of GWAS Discovery: Biology, Function, and Translation

Peter M. Visscher et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2017)

Article Genetics & Heredity

The Genetic Architecture of Gene Expression in Peripheral Blood

Luke R. Lloyd-Jones et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2017)

Article Genetics & Heredity

The contribution of rare variation to prostate cancer heritability

Nicholas Mancuso et al.

NATURE GENETICS (2016)

Article Biochemistry & Molecular Biology

Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants

Lawrence H. Uricchio et al.

GENOME RESEARCH (2016)

Article Biochemistry & Molecular Biology

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112151)

G. Davies et al.

MOLECULAR PSYCHIATRY (2016)

Article Multidisciplinary Sciences

The genetic architecture of type 2 diabetes

Christian Fuchsberger et al.

NATURE (2016)

Article Genetics & Heredity

A reference panel of 64,976 haplotypes for genotype imputation

Shane McCarthy et al.

NATURE GENETICS (2016)

Article Multidisciplinary Sciences

Detection of human adaptation during the past 2000 years

Yair Field et al.

SCIENCE (2016)

Article Biochemical Research Methods

Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes

Jerome Kelleher et al.

PLOS COMPUTATIONAL BIOLOGY (2016)

Article Genetics & Heredity

Leveraging Distant Relatedness to Quantify Human Mutation and Gene-Conversion Rates

Pier Francesco Palamara et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2015)

Article Multidisciplinary Sciences

The UK10K project identifies rare variants in health and disease

Klaudia Walter et al.

NATURE (2015)

Article Multidisciplinary Sciences

Genetic studies of body mass index yield new insights for obesity biology

Adam E. Locke et al.

NATURE (2015)

Article Genetics & Heredity

Population genetic differentiation of height and body mass index across Europe

Matthew R. Robinson et al.

NATURE GENETICS (2015)

Article Genetics & Heredity

An atlas of genetic correlations across human diseases and traits

Brendan Bulik-Sullivan et al.

NATURE GENETICS (2015)

Article Biochemistry & Molecular Biology

Genome-wide signals of positive selection in human evolution

David Enard et al.

GENOME RESEARCH (2014)

Article Genetics & Heredity

The deleterious mutation load is insensitive to recent population history

Yuval B. Simons et al.

NATURE GENETICS (2014)

Review Neurosciences

Large-scale genomics unveils the genetic architecture of psychiatric disorders

Jacob Gratten et al.

NATURE NEUROSCIENCE (2014)

Article Agriculture, Dairy & Animal Science

A class of Bayesian methods to combine large numbers of genotyped and non-genotyped animals for whole-genome analyses

Rohan L. Fernando et al.

GENETICS SELECTION EVOLUTION (2014)

Letter Genetics & Heredity

Estimation of SNP Heritability from Dense Genotype Data

[Anonymous]

AMERICAN JOURNAL OF HUMAN GENETICS (2013)

Review Genetics & Heredity

Whole-Genome Regression and Prediction Methods Applied to Plant and Animal Breeding

Gustavo de los Campos et al.

GENETICS (2013)

Article Genetics & Heredity

SLiM: Simulating Evolution with Selection and Linkage

Philipp W. Messer

GENETICS (2013)

Review Physiology

Determinants of intra-specific variation in basal metabolic rate

Marek Konarzewski et al.

JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY (2013)

Article Genetics & Heredity

Improved Heritability Estimation from Genome-wide SNPs

Doug Speed et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2012)

Review Biochemistry & Molecular Biology

Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses

P. M. Visscher et al.

MOLECULAR PSYCHIATRY (2012)

Article Multidisciplinary Sciences

An integrated map of genetic variation from 1,092 human genomes

David M. Altshuler et al.

NATURE (2012)

Article Genetics & Heredity

Evidence of widespread selection on standing variation in Europe at height-associated SNPs

Michael C. Turchin et al.

NATURE GENETICS (2012)

Article Genetics & Heredity

Estimating Missing Heritability for Disease from Genome-wide Association Studies

Sang Hong Lee et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Article Genetics & Heredity

GCTA: A Tool for Genome-wide Complex Trait Analysis

Jian Yang et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2011)

Article Statistics & Probability

BAYESIAN VARIABLE SELECTION REGRESSION FOR GENOME-WIDE ASSOCIATION STUDIES AND OTHER LARGE-SCALE PROBLEMS

Yongtao Guan et al.

ANNALS OF APPLIED STATISTICS (2011)

Article Biochemical Research Methods

Extension of the bayesian alphabet for genomic selection

David Habier et al.

BMC BIOINFORMATICS (2011)

Article Genetics & Heredity

Genome partitioning of genetic variation for complex traits using common SNPs

Jian Yang et al.

NATURE GENETICS (2011)

Article Multidisciplinary Sciences

Demographic history and rare allele sharing among human populations

Simon Gravel et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Classic Selective Sweeps Were Rare in Recent Human Evolution

Ryan D. Hernandez et al.

SCIENCE (2011)

Review Biochemistry & Molecular Biology

The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation

Jonathan K. Pritchard et al.

CURRENT BIOLOGY (2010)

Article Multidisciplinary Sciences

Integrating common and rare genetic variation in diverse human populations

David M. Altshuler et al.

NATURE (2010)

Article Genetics & Heredity

Common SNPs explain a large proportion of the heritability for human height

Jian Yang et al.

NATURE GENETICS (2010)

Article Multidisciplinary Sciences

Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency

Angela M. Hancock et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

Adam Eyre-Walker

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Multidisciplinary Sciences

Finding the missing heritability of complex diseases

Teri A. Manolio et al.

NATURE (2009)

Article Statistics & Probability

The optimal discovery procedure: a new approach to simultaneous significance testing

John D. Storey

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY (2007)

Review Biology

Theoretical models of selection and mutation on quantitative traits

T Johnson et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2005)

Article Genetics & Heredity

Controlling the proportion of false positives in multiple dependent tests

RL Fernando et al.

GENETICS (2004)

Letter Dermatology

Genetic basis of male pattern baldness

DR Nyholt et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2003)

Article Genetics & Heredity

Are rare variants responsible for susceptibility to complex diseases?

JK Pritchard

AMERICAN JOURNAL OF HUMAN GENETICS (2001)