期刊
MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS XI
卷 8615, 期 -, 页码 -出版社
SPIE-INT SOC OPTICAL ENGINEERING
DOI: 10.1117/12.2004041
关键词
Stationary fluidics; molecular diagnostics; beads; chip-based PCR
资金
- German Ministry of Education and Research (BMBF) under MinoLab [16SV4028]
Commonly, microfluidic devices are based on the movement of fluids. For molecular diagnostics assays which often include steps like PCR, this practically always involves a more or less complicated set of external pumps, valves and liquid controls. In the presented paper, we follow a different approach in which the fluid after sample introduction remains stationary and the main bioactive sample molecules are moved through a chain of reaction compartments which contain the different reagents necessary for the assay. The big advantage of this concept is the lack of any external fluid actuation/control. Results on sample carry-over experiments and complete assays will be given.
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