期刊
NATURAL PRODUCT RESEARCH
卷 33, 期 24, 页码 3577-3581出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1483927
关键词
Curcumin; genistein; rhodesain; drug combination studies; synergism
资金
- University of Messina
Curcumin and genistein are two natural products obtained from Curcuma longa L. and soybeans, endowed with many biological properties. Within the last years they were shown to possess also a promising antitrypanosomal activity. In the present paper, we investigated the activity of both curcumin and genistein against rhodesain, the main cysteine protease of Trypanosoma brucei rhodesiense; drug combination studies, according to Chou and Talalay method, allowed us to demonstrate a potent synergistic effect for the combination curcumin-genistein. As a matter of fact, with our experiments we observed that the combination index of curcumin-genistein is?
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据