期刊
NATURAL PRODUCT RESEARCH
卷 33, 期 9, 页码 1357-1373出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1474467
关键词
Furofuran lignan; source; phytochemistry; biological activities
资金
- National Science Foundation of China (NSFC) [21362035, 21462040]
- Initial Foundation of Scientific Research for the introduction of talents from Southwest Forestry University [20130916]
- Opening Research Foundation from Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University [KLE201807]
Furofuran lignans containing the 2,6-diaryl-3,7-dioxabicyclo[3.3.0]octane skeleton, represent one of the major subclasses of the lignan family of natural products. Furofuran lignans feature a wide variety of structures due to different substituents at aryl groups and diverse configurations at furofuran ring. Moreover, they exhibit a wide range of significant biological activities, including antioxidant, anti-inflammatory, cytotoxic, and antimicrobial activities. This review summarizes source, phytochemistry, and biological activities of 137 natural furofuran lignans isolated from 53 species in 41 genera of 27 plant families for the last 20 years, which provides a comprehensive information for further research of these furofuran lignans as potential pharmaceutical agents. [GRAPHICS] .
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