期刊
NATURAL PRODUCT RESEARCH
卷 33, 期 3, 页码 328-334出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1448980
关键词
Schisandra glaucescens; triterpenoids; lignans; cytotoxicity
资金
- National Natural Science Foundation of China [31770380, 21572073, 31270394]
- Fundamental Research Funds for the Central Universities [2016YXMS150]
Two new triterpenoids, 24(E)-3 alpha,12 alpha-dihydroxyl-lanost-9(11),24-dien-26-oid acid (1) and 3,4-seco-24(Z)-6 alpha,7 beta-dihydroxyl-cycloart-4(28),24-dien-3,26-dioic-3-methyl ester (2), and ten known ones (3-12), together with eight lignans (13-20), were isolated from the stems of Schisandra glaucescens. Their structures were established on the basis of extensive spectroscopic analyses. Compounds 1-3, 5-7, 9, 11-13 and 15-18 were isolated from this species for the first time. 1 and 2 were evaluated for their in vitro cytotoxicities against the mouse cancer B16 cell line, human cancer HepG2 and MCF7 cell lines by MTT assay. [GRAPHICS] .
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