期刊
NATURAL PRODUCT RESEARCH
卷 33, 期 9, 页码 1262-1268出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2018.1470173
关键词
Ascidian-derived fungus; Penicillium; isochromane; antibacteria
资金
- National Natural Science Foundation of China [21272286, 41606167]
- China's Marine Commonweal Research Project [201305017]
Seven polyketides, including two new isochromanes, penisochromanes A and B (1 and 2), as well as five known compounds were obtained from an ascidian-derived fungus Penicillium sp. 4829. Their structures were identified by extensive spectroscopic analyses. The structures of compounds 1 and 3 were further determined by the X-ray crystallography. Compounds 1 and 2 were the first example of isochromane with three adjacent oxy substituents in natural source. Compound 4 exhibited selective activities against two Gram-positive bacteria Staphylococcus aureus and Bacillus subtilis, with MIC values 6.25 and 12.5 mu M, respectively. [GRAPHICS] .
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据