期刊
MYCOSES
卷 61, 期 11, 页码 857-860出版社
WILEY
DOI: 10.1111/myc.12825
关键词
anal sex; fluconazole maintenance tharapy; multiple site colonisation; Recurrent vulvovaginal candidosis; sexual habits; vulvovaginal candidiasis
Objective This study analyses a relation between sexual habits and the presence of Candida in extra-genital locations as well as a potential effect on therapy response. Material and MethodsResultsCandida cultures were obtained from mouth, nose, anus, urine and perineum of 117 women enrolled in a RVVC treatment trial (ReCiDiF). Sexual behaviour and carriage rates of extra-genital Candida of women responding well to treatment were compared to that of non-responders. Most respondents were heterosexual. All but one practiced vaginal sex. Regular receptive oral sex was not related to multiple site colonisation with Candida (OR=1.27; CI95% 0.36-4.48), nor to non-response to therapy (OR=1.3; CI 95% 0.41-4.73). Also, masturbation was not related to response to therapy (OR 0.8; CI95% 0.31-1.84), nor was anal sex (OR=0.54; CI95% 0.11-2.72). ConclusionNeither oral nor casual anal sex, nor masturbation can be held responsible for the association of the multiple site/anal colonisation with Candida and inferior response to fluconazole maintenance therapy. Changing sexual behaviour during fluconazole maintenance treatment for RVVC in otherwise healthy women should not be advocated. Also, treatment of asymptomatic sexual partners of women with RVVC is not recommended.
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