期刊
AIDS AND BEHAVIOR
卷 17, 期 8, 页码 2725-2731出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10461-013-0503-3
关键词
Social stigma; Depression; Antiretroviral; therapy; Highly active; HIV; Uganda
资金
- NIAID NIH HHS [P30 AI027763, P30 AI-027763] Funding Source: Medline
- NIMH NIH HHS [K23 MH-096620, K24 MH-087227, K23 MH-079713-03S1, K23 MH-087228, K24 MH087227, R01 MH-054907, K23 MH087228, R01 MH054907, K23 MH-079713, K23 MH096620, K23 MH079713] Funding Source: Medline
Program implementers and qualitative researchers have described how increasing availability of HIV antiretroviral therapy (ART) is associated with improvements in psychosocial health and internalized stigma. To determine whether, and through what channels, ART reduces internalized stigma, we analyzed data from 262 HIV-infected, treatment-na < ve persons in rural Uganda followed from ART initiation over a median of 3.4 years. We fitted Poisson regression models with cluster-correlated robust estimates of variance, specifying internalized stigma as the dependent variable, adjusting for time on treatment as well as socio-demographic, clinical, and psychosocial variables. Over time on treatment, internalized stigma declined steadily, with the largest decline observed during the first 2 years of treatment. This trend remained statistically significant after multivariable adjustment (chi(2) = 28.3; P = 0.03), and appeared to be driven by ART-induced improvements in HIV symptom burden, physical and psychological wellbeing, and depression symptom severity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据