4.2 Article

NANO-COPPER CATALYZED THREE-COMPONENT TANDEM CYCLOADDITION AND N-ALKYLATION REACTION FROM AMINOPHENYLACETYLENES, SODIUM AZIDE AND ALKYL HALIDES

期刊

HETEROCYCLES
卷 91, 期 10, 页码 1964-1971

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.3987/COM-15-13277

关键词

Nano-Copper Catalysis; Cycloaddition Reaction; N-Alkylation Reaction; Tandem Reaction; Multicomponent Reaction

资金

  1. Natural Science Foundation of China [20702042, 21262028]
  2. Program for Changjiang Scholars and Innovative Research Teams in Universities of the Ministry of Education of China [IRT1177]
  3. Natural Science Foundation of Gansu Province [1208RJZA140]

向作者/读者索取更多资源

Nano-copper catalyzed one-pot three-component method is realized from aminophenylacetylenes, sodium azide and alkyl halides via tandem 3+2 dipolar cycloaddition reaction and N-alkylation reaction. This synthetic process gave the product of 1-alkyl-4-(N-alkylaminophenyl)-1H-1,2,3-triazoles in good yields.

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