期刊
MOLECULES
卷 23, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/molecules23071665
关键词
interleukin-33; allergic diseases; target therapy; asthma; Th2-type immunity
资金
- National Natural Science Foundation of China [31660287]
Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions.
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