相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Exogenous ghrelin administration increases alcohol self-administration and modulates brain functional activity in heavy-drinking alcohol-dependent individuals
M. Farokhnia et al.
MOLECULAR PSYCHIATRY (2018)
Pharmacokinetics and pharmacodynamics of PF-05190457: The first oral ghrelin receptor inverse agonist to be profiled in healthy subjects
William S. Denney et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2017)
From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation
Ken Howick et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Altering ethanol pharmacokinetics to treat alcohol use disorder: Can you teach an old dog new tricks?
Carolina L. Haass-Koffler et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2017)
Biobehavioral effects of baclofen in anxious alcohol-dependent individuals: a randomized, double-blind, placebo-controlled, laboratory study
M. Farokhnia et al.
TRANSLATIONAL PSYCHIATRY (2017)
Ghrelin is Supressed by Intravenous Alcohol and is Related to Stimulant and Sedative Effects of Alcohol
Elizabeth Ralevski et al.
ALCOHOL AND ALCOHOLISM (2017)
Sub-chronic Ghrelin Receptor Blockade Attenuates Alcohol- and Amphetamine-Induced Locomotor Stimulation in Mice
Petra Suchankova et al.
ALCOHOL AND ALCOHOLISM (2016)
Pharmacological characterization of the first in class clinical candidate PF-05190457: a selective ghrelin receptor competitive antagonist with inverse agonism that increases vagal afferent firing and glucose-dependent insulin secretion ex vivo
J. Kong et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Ghrelin receptor (GHS-R1A) antagonism alters preference for ethanol and sucrose in a concentration-dependent manner in prairie voles
J. R. Stevenson et al.
PHYSIOLOGY & BEHAVIOR (2016)
Development and validation of an UPLC-MS/MS assay for quantitative analysis of the ghrelin receptor inverse agonist PF-5190457 in human or rat plasma and rat brain
Mwlod Ghareeb et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2015)
Differential effects of ghrelin antagonists on alcohol drinking and reinforcement in mouse and rat models of alcohol dependence
Juan L. Gomez et al.
NEUROPHARMACOLOGY (2015)
GHS-R1A antagonism reduces alcohol but not sucrose preference in prairie voles
J. R. Stevenson et al.
PHYSIOLOGY & BEHAVIOR (2015)
A preliminary double-blind, placebo-controlled randomized study of baclofen effects in alcoholic smokers
Lorenzo Leggio et al.
PSYCHOPHARMACOLOGY (2015)
Elevated ratio of acylated to unacylated ghrelin in children and young adults with Prader-Willi syndrome
R. J. Kuppens et al.
ENDOCRINE (2015)
The Effects of Ghrelin Antagonists [D-Lys3]-GHRP-6 or JMV2959 on Ethanol, Water, and Food Intake in C57BL/6J Mice
Juan L. Gomez et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)
Intravenous Ghrelin Administration Increases Alcohol Craving in Alcohol-Dependent Heavy Drinkers: A Preliminary Investigation
Lorenzo Leggio et al.
BIOLOGICAL PSYCHIATRY (2014)
Pharmacotherapy for Adults With Alcohol Use Disorders in Outpatient Settings A Systematic Review and Meta-analysis
Daniel E. Jonas et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)
Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate
Samit K. Bhattacharya et al.
ACS MEDICINAL CHEMISTRY LETTERS (2014)
Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus
P. Anil Kumar et al.
FRONTIERS IN ENDOCRINOLOGY (2014)
The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects
Jenny Tong et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2013)
Ghrelin Increases GABAergic Transmission and Interacts with Ethanol Actions in the Rat Central Nucleus of the Amygdala
Maureen T. Cruz et al.
NEUROPSYCHOPHARMACOLOGY (2013)
Ghrelin Receptor (GHS-R1A) Antagonism Suppresses Both Alcohol Consumption and the Alcohol Deprivation Effect in Rats following Long-Term Voluntary Alcohol Consumption
Petra Suchankova et al.
PLOS ONE (2013)
A human laboratory pilot study with baclofen in alcoholic individuals
Lorenzo Leggio et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2013)
Anti-ghrelin immunoglobulins modulate ghrelin stability and its orexigenic effect in obese mice and humans
Kuniko Takagi et al.
NATURE COMMUNICATIONS (2013)
Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats
Sara Landgren et al.
ADDICTION BIOLOGY (2012)
Ghrelin system in alcohol-dependent subjects: role of plasma ghrelin levels in alcohol drinking and craving
Lorenzo Leggio et al.
ADDICTION BIOLOGY (2012)
Identification of spirocyclic piperidine-azetidine inverse agonists of the ghrelin receptor
Daniel W. Kung et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Alcohol Intake and Its Effect on Some Appetite-Regulating Hormones in Man: Influence of Gastroprotection with Sucralfate
Jan Calissendorff et al.
ENDOCRINE RESEARCH (2012)
The Loss of Metabolic Control on Alcohol Drinking in Heavy Drinking Alcohol-Dependent Subjects
Philippe de Timary et al.
PLOS ONE (2012)
The association of the appetitive peptide acetylated ghrelin with alcohol craving in early abstinent alcohol dependent individuals
Anne Koopmann et al.
PSYCHONEUROENDOCRINOLOGY (2012)
Current and Promising Pharmacotherapies, and Novel Research Target Areas in the Treatment of Alcohol Dependence: A Review
Steven M. Edwards et al.
CURRENT PHARMACEUTICAL DESIGN (2011)
The role of the central ghrelin system in reward from food and chemical drugs
Suzanne L. Dickson et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2011)
Ghrelin Receptor Antagonism Decreases Alcohol Consumption and Activation of Perioculomotor Urocortin-Containing Neurons
Simranjit Kaur et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2010)
ROLE OF THE GHRELIN SYSTEM IN ALCOHOLISM: ACTING ON THE GROWTH HORMONE SECRETAGOGUE RECEPTOR TO TREAT ALCOHOL-RELATED DISORDERS
Lorenzo Leggio
DRUG NEWS & PERSPECTIVES (2010)
Suppression of alcohol self-administration and reinstatement of alcohol seeking by melanin-concentrating hormone receptor 1 (MCH1-R) antagonism in Wistar rats
Andrea Cippitelli et al.
PSYCHOPHARMACOLOGY (2010)
GOAT links dietary lipids with the endocrine control of energy balance
Henriette Kirchner et al.
NATURE MEDICINE (2009)
Requirement of central ghrelin signaling for alcohol reward
Elisabet Jerlhag et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine
Elisabet Jerlhag
ADDICTION BIOLOGY (2008)
Alcohol dependence is associated with reduced plasma and fundic ghrelin levels
A. Badaoui et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2008)
Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men
Jianhua Liu et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
The modified Trait and State Food-Cravings Questionnaires: Development and validation of a general index of food craving
Ilse M. T. Nijs et al.
APPETITE (2007)
Alcohol administration acutely inhibits ghrelin secretion in an experiment involving psychosocial stress
Ulrich S. Zimmermann et al.
ADDICTION BIOLOGY (2007)
Characterisation of proghrelin peptides in mammalian tissue and plasma
Angela S. Bang et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Alcohol ingestion does not affect serum levels of peptide YY but decreases both total and octanoylated ghrelin levels in healthy subjects
Jan Calissendorff et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2006)
Relationship between Ghrelin levels, alcohol craving, and nutritional status in current alcoholic patients
Giovanni Addolorato et al.
ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH (2006)
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature
J Pantel et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Ghrelin levels are increased in alcoholism
T Kraus et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2005)
Inhibitory effect of alcohol on ghrelin secretion in normal man
J Calissendorff et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2005)
The reinstatement model of drug relapse: history, methodology and major findings
Y Shaham et al.
PSYCHOPHARMACOLOGY (2003)
Structural divergence of human ghrelin - Identification of multiple ghrelin-derived molecules produced by post-translational processing
H Hosoda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
分享论文
