期刊
MOLECULAR ORAL MICROBIOLOGY
卷 33, 期 4, 页码 271-282出版社
WILEY
DOI: 10.1111/omi.12228
关键词
dental plaque; innate immunity; periodontal diseases; tobacco; vasculature
资金
- U.S. Department of Health and Human Services via the National Institute for Dental and Craniofacial Research
- U.S. Department of Health and Human Services via the National Institute for General Medical Sciences
Cigarette smoking presents oral health professionals with a clinical and research conundrum: reduced periodontal vascular responsiveness to the oral biofilm accompanied by increased susceptibility to destructive periodontal diseases. This presents a significant problem, hampering diagnosis and complicating treatment planning. The aim of this review is to summarize contemporary hypotheses that help to explain mechanistically the phenomenon of a suppressed bleeding response to dysbiotic plaque in the periodontia of smokers. The influence of smoke exposure on angiogenesis, innate cell function, the production of inflammatory mediators including cytokines and proteases, tobacco-bacteria interactions, and potential genetic predisposition are discussed.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据