相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Branched-chain amino acids differently modulate catabolic and anabolic states in mammals: a pharmacological point of view
Francesco Bifari et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Metabolic Fate of Branched-Chain Amino Acids During Adipogenesis, in Adipocytes From Obese Mice and C2C12 Myotubes
Isabela Estrada-Alcalde et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2017)
International Society of Sports Nutrition Position Stand: protein and exercise
Ralf Jager et al.
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2017)
International society of sports nutrition position stand: diets and body composition
Alan A. Aragon et al.
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2017)
Leucine Supplementation Differently Modulates Branched-Chain Amino Acid Catabolism, Mitochondrial Function and Metabolic Profiles at the Different Stage of Insulin Resistance in Rats on High-Fat Diet
Rui Liu et al.
NUTRIENTS (2017)
Leucine-induced anabolic-catabolism: two sides of the same coin
Nicholas P. Gannon et al.
AMINO ACIDS (2016)
Ketoisocaproic acid, a metabolite of leucine, suppresses insulin- stimulated glucose transport in skeletal muscle cells in a BCAT2-dependent manner
Mahshid Moghei et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2016)
Determination of the safety of leucine supplementation in healthy elderly men
Betina Rasmussen et al.
AMINO ACIDS (2016)
Leucine stimulates PPARβ/δ-dependent mitochondrial biogenesis and oxidative metabolism with enhanced GLUT4 content and glucose uptake in myotubes
Jamie K. Schnuck et al.
BIOCHIMIE (2016)
Branched-Chain Amino Acids and Insulin Metabolism: The Insulin Resistance Atherosclerosis Study (IRAS)
C. Christine Lee et al.
DIABETES CARE (2016)
Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans
Jheelam Banerjee et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2016)
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
Cholsoon Jang et al.
NATURE MEDICINE (2016)
Associations among the plasma amino acid profile, obesity, and glucose metabolism in Japanese adults with normal glucose tolerance
Chisa Takashina et al.
NUTRITION & METABOLISM (2016)
Suppression of Endogenous Glucose Production by Isoleucine and Valine and Impact of Diet Composition
Isabel Arrieta-Cruz et al.
NUTRIENTS (2016)
Defining meal requirements for protein to optimize metabolic roles of amino acids
Donald K. Layman et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2015)
Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk
Marie Michele Boulet et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2015)
Leucine supplementation does not affect protein turnover and impairs the beneficial effects of endurance training on glucose homeostasis in healthy mice
Jose M. Costa Junior et al.
AMINO ACIDS (2015)
Diabetes risk and amino acid profiles: cross-sectional and prospective analyses of ethnicity, amino acids and diabetes in a South Asian and European cohort from the SABRE (Southall And Brent REvisited) Study
Therese Tillin et al.
DIABETOLOGIA (2015)
Supplemental Protein in Support of Muscle Mass and Health: Advantage Whey
Michaela C. Devries et al.
JOURNAL OF FOOD SCIENCE (2015)
Whey Protein Supplementation Does Not Alter Plasma Branched-Chained Amino Acid Profiles but Results in Unique Metabolomics Patterns in Obese Women Enrolled in an 8-Week Weight Loss Trial
Brian D. Piccolo et al.
JOURNAL OF NUTRITION (2015)
18-Carbon polyunsaturated fatty acids ameliorate palmitate-induced inflammation and insulin resistance in mouse C2C12 myotubes
Pei-Yin Chen et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2015)
Leucine amplifies the effects of metformin on insulin sensitivity and glycemic control in diet-induced obese mice
Lizhi Fu et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2015)
In vitro anti-hyperglycemic activity of 4-hydroxyisoleucine derivatives
Venkateswarlu Korthikunta et al.
PHYTOMEDICINE (2015)
Association between insulin resistance and plasma amino acid profile in non-diabetic Japanese subjects
Chizumi Yamada et al.
JOURNAL OF DIABETES INVESTIGATION (2015)
Dietary stimulators of GLUT4 expression and translocation in skeletal muscle: A mini-review
Nicholas P. Gannon et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2015)
4-Hydroxyisoleucine improves insulin resistance by promoting mitochondrial biogenesis and act through AMPK and Akt dependent pathway
Arun Kumar Rawat et al.
FITOTERAPIA (2014)
Dietary stimulators of the PGC-1 superfamily and mitochondrial biosynthesis in skeletal muscle. A mini-review
Roger A. Vaughan et al.
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY (2014)
4-Hydroxyisoleucine ameliorates fatty acid-induced insulin resistance and inflammatory response in skeletal muscle cells
Chandan Kumar Maurya et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)
Branched-chain amino acids in metabolic signalling and insulin resistance
Christopher J. Lynch et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells
Jose L. Areta et al.
NUTRITION RESEARCH (2014)
PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle
Yukino Hatazawa et al.
PLOS ONE (2014)
Leucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes
Chunzi Liang et al.
JOURNAL OF NUTRITION AND METABOLISM (2014)
Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
Denise E. Lackey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2013)
Leucine treatment enhances oxidative capacity through complete carbohydrate oxidation and increased mitochondrial density in skeletal muscle cells
Roger A. Vaughan et al.
AMINO ACIDS (2013)
A dipeptide and an amino acid present in whey protein hydrolysate increase translocation of GLUT-4 to the plasma membrane in Wistar rats
P. N. Morato et al.
FOOD CHEMISTRY (2013)
Regulation of mTORC1 and its impact on gene expression at a glance
Mathieu Laplante et al.
JOURNAL OF CELL SCIENCE (2013)
Whey Protein Supplementation During Resistance Training Augments Lean Body Mass
Jeff S. Volek et al.
JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION (2013)
Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3
Julia Brenmoehl et al.
MITOCHONDRION (2013)
Chronic leucine supplementation increases body weight and insulin sensitivity in rats on high-fat diet likely by promoting insulin signaling in insulin-target tissues
Xiang Li et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2013)
Leucine Supplementation Protects from Insulin Resistance by Regulating Adiposity Levels
Elke Binder et al.
PLOS ONE (2013)
Determination of the tolerable upper intake level of leucine in acute dietary studies in young men
Rajavel Elango et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2012)
Leucine and mTORC1: a complex relationship
Kayleigh M. Dodd et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice
Hongliang Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Interplay between Lipids and Branched-Chain Amino Acids in Development of Insulin Resistance
Christopher B. Newgard
CELL METABOLISM (2012)
Leucine supplementation chronically improves muscle protein synthesis in older adults consuming the RDA for protein
Shanon L. Casperson et al.
CLINICAL NUTRITION (2012)
Hypothalamic Leucine Metabolism Regulates Liver Glucose Production
Ya Su et al.
DIABETES (2012)
Metabolic Signatures of Insulin Resistance in 7,098 Young Adults
Peter Wurtz et al.
DIABETES (2012)
4-Hydroxyisoleucine stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells via phosphatidylinositol-3-kinase-dependent pathway
Natasha Jaiswal et al.
EUROPEAN JOURNAL OF NUTRITION (2012)
PGC-1α and exercise in the control of body weight
S. Summermatter et al.
INTERNATIONAL JOURNAL OF OBESITY (2012)
Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion
Pierre-Gilles Blanchard et al.
JOURNAL OF LIPID RESEARCH (2012)
A Proposal for an Upper Limit of Leucine Safe Intake in Healthy Adults
Luc Cynober et al.
JOURNAL OF NUTRITION (2012)
Leucine induces myofibrillar protein accretion in cultured skeletal muscle through mTOR dependent and -independent control of myosin heavy chain mRNA levels
Astrid Haegens et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2012)
Effects of leucine supplementation and resistance exercise on dexamethasone-induced muscle atrophy and insulin resistance in rats
Humberto Nicastro et al.
NUTRITION (2012)
Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice
Antje Bruckbauer et al.
NUTRITION & METABOLISM (2012)
Enteral leucine supplementation increases protein synthesis in skeletal and cardiac muscles and visceral tissues of neonatal pigs through mTORC1-dependent pathways
Agus Suryawan et al.
PEDIATRIC RESEARCH (2012)
PGC-1 coactivators in the control of energy metabolism
Chang Liu et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2011)
Leucine-enriched essential amino acid supplementation during moderate steady state exercise enhances postexercise muscle protein synthesis
Stefan M. Pasiakos et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2011)
An amino acid mixture improves glucose tolerance and insulin signaling in Sprague-Dawley rats
Jeffrey R. Bernard et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Leucine-stimulated mTOR signaling is partly attenuated in skeletal muscle of chronically uremic rats
Yu Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
Differential effects of long-term leucine infusion on tissue protein synthesis in neonatal pigs
Fiona A. Wilson et al.
AMINO ACIDS (2011)
Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity
Serge Summermatter et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
Richard C. Scarpulla
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Nutrient provision increases signalling and protein synthesis in human skeletal muscle after repeated sprints
Vernon G. Coffey et al.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY (2011)
Body weight and energy homeostasis was not affected in C57BL/6 mice fed high whey protein or leucine-supplemented low-fat diets
Anne Noatsch et al.
EUROPEAN JOURNAL OF NUTRITION (2011)
Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance
Michele Balage et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2011)
Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism
Yazmin Macotela et al.
PLOS ONE (2011)
Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells
Philip J. Atherton et al.
AMINO ACIDS (2010)
Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs
Yulong Yin et al.
AMINO ACIDS (2010)
Branched-Chain Amino Acid Supplementation Promotes Survival and Supports Cardiac and Skeletal Muscle Mitochondrial Biogenesis in Middle-Aged Mice
Giuseppe D'Antona et al.
CELL METABOLISM (2010)
Insulin resistance is associated with a metabolic profile of altered protein metabolism in Chinese and Asian-Indian men
E. S. Tai et al.
DIABETOLOGIA (2010)
Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance
Pengxiang She et al.
JOURNAL OF APPLIED PHYSIOLOGY (2010)
Leucine modulates contraction- and insulin-stimulated glucose transport and upstream signaling events in rat skeletal muscle
Nobumasa Iwanaka et al.
JOURNAL OF APPLIED PHYSIOLOGY (2010)
Stimulation of Muscle Protein Synthesis by Prolonged Parenteral Infusion of Leucine Is Dependent on Amino Acid Availability in Neonatal Pigs
Fiona A. Wilson et al.
JOURNAL OF NUTRITION (2010)
Isoleucine Prevents the Accumulation of Tissue Triglycerides and Upregulates the Expression of PPARα and Uncoupling Protein in Diet-Induced Obese Mice
Junko Nishimura et al.
JOURNAL OF NUTRITION (2010)
Leucine Supplementation of a Low-Protein Meal Increases Skeletal Muscle and Visceral Tissue Protein Synthesis in Neonatal Pigs by Stimulating mTOR-Dependent Translation Initiation
Roberto Murgas Torrazza et al.
JOURNAL OF NUTRITION (2010)
Excess Leucine Intake Enhances Muscle Anabolic Signaling but Not Net Protein Anabolism in Young Men and Women
Erin L. Glynn et al.
JOURNAL OF NUTRITION (2010)
Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway
Eliane Filiputti et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2010)
Chronic leucine supplementation improves glycemic control in etiologically distinct mouse models of obesity and diabetes mellitus
Kaiying Guo et al.
NUTRITION & METABOLISM (2010)
Plasma Metabolomic Profiles Reflective of Glucose Homeostasis in Non-Diabetic and Type 2 Diabetic Obese African-American Women
Oliver Fiehn et al.
PLOS ONE (2010)
A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
Christopher B. Newgard et al.
CELL METABOLISM (2009)
Relationships Between Circulating Metabolic Intermediates and Insulin Action in Overweight to Obese, Inactive Men and Women
Kim M. Huffman et al.
DIABETES CARE (2009)
SIRT1 Controls the Transcription of the Peroxisome Proliferator-activated Receptor-γ Co-activator-1α (PGC-1α) Gene in Skeletal Muscle through the PGC-1α Autoregulatory Loop and Interaction with MyoD
Ramon Amat et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Leucine modulation of mitochondrial mass and oxygen consumption in skeletal muscle cells and adipocytes
Xiaocun Sun et al.
NUTRITION & METABOLISM (2009)
Mechanisms of human insulin resistance and thiazolidinedione-mediated insulin sensitization
D. D. Sears et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation
Agus Suryawan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle
Hans C. Dreyer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism in glucose-intolerant and diabetic mice
Osamu Ikehara et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2008)
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations
Jaclyn LoPiccolo et al.
DRUG RESISTANCE UPDATES (2008)
Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells
Teresa Coll et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Antagonistic effects of leucine and glutamine on the mTOR pathway in myogenic C2C12 cells
L. Deldicque et al.
AMINO ACIDS (2008)
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism
Pengxiang She et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover
Virginie Mieulet et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
Sibylle Jaeger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hypoglycemic effect of isoleucine involves increased muscle glucose uptake and whole body glucose oxidation and decreased hepatic gluconeogenesis
Masako Doi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2007)
Leucine stimulates mammalian target of rapamycin signaling in C2C12 myoblasts in part through inhibition of adenosine monophosphate-activated protein kinase
M. Du et al.
JOURNAL OF ANIMAL SCIENCE (2007)
Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms
Yiying Zhang et al.
DIABETES (2007)
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
Marie Lagouge et al.
CELL (2006)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Upstream of the mammalian target of rapamycin: do all roads pass through mTOR?
M. N. Corradetti et al.
ONCOGENE (2006)
Regulation of protein synthesis by leucine starvation involves distinct mechanisms in mouse C2C12 myoblasts and myotubes
Jeremie Talvas et al.
JOURNAL OF NUTRITION (2006)
The underappreciated role of muscle in health and disease
Robert R. Wolfe
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
Branched-chain amino acids: Enzyme and substrate regulation
JT Brosnan et al.
JOURNAL OF NUTRITION (2006)
Ribosomal protein S6 phosphorylation: from protein synthesis to cell size
Igor Ruvinsky et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Isoleucine, a blood glucose-lowering amino acid, increases glucose uptake in rat skeletal muscle in the absence of increases in AMP-activated protein kinase activity
M Doi et al.
JOURNAL OF NUTRITION (2005)
Branched-chain amino acids improve glucose metabolism in rats with liver cirrhosis
S Nishitani et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators
N Gleyzer et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Leucine reduces the duration of insulin-induced PI 3-kinase activity in rat skeletal muscle
JI Baum et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation
DR Bolster et al.
JOURNAL OF NUTRITION (2004)
Exercise promotes BCAA catabolism: Effects of BCAA supplementation on skeletal muscle during exercise
Y Shimomura et al.
JOURNAL OF NUTRITION (2004)
Potential approaches to the assessment of amino acid adequacy in rats: A progress report
R Sakai et al.
JOURNAL OF NUTRITION (2004)
Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes
M Doi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
Leucine promotes glucose uptake in skeletal muscles of rats
S Nishitani et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation
HH Zong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms
R Kobayashi et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2002)
Transcriptional activators and coactivators in the nuclear control of mitochondrial function in mammalian cells
RC Scarpulla
GENE (2002)
A unique PPARγ ligand with potent insulin-sensitizing yet weak adipogenic activity
S Rocchi et al.
MOLECULAR CELL (2001)
Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine
JC Anthony et al.
JOURNAL OF NUTRITION (2001)
Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age
D Dardevet et al.
JOURNAL OF NUTRITION (2000)
4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle
OJ Shah et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2000)
分享论文
