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HUMAN MOLECULAR GENETICS (2013)
The Role of Metallothionein in Oxidative Stress
Branislav Ruttkay-Nedecky et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Mammalian Target of Rapamycin (mTor) Mediates Tau Protein Dyshomeostasis IMPLICATION FOR ALZHEIMER DISEASE
Zhi Tang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage
Patrick Wunderlich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
mTOR: at the crossroads of aging, chaperones, and Alzheimer's disease
Gunnar K. Gouras
JOURNAL OF NEUROCHEMISTRY (2013)
Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells
Pamela Urrutia et al.
JOURNAL OF NEUROCHEMISTRY (2013)
Neuroinflammatory phenotype in early Alzheimer's disease
Tiffany L. Sudduth et al.
NEUROBIOLOGY OF AGING (2013)
Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease
Chuang Guo et al.
NEUROBIOLOGY OF AGING (2013)
Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain
Chuang Guo et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
Metal dyshomeostasis and oxidative stress in Alzheimer's disease
Mark A. Greenough et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Oxidative Stress and the Pathogenesis of Alzheimer's Disease
Yan Zhao et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
MicroRNA-486-3p Regulates γ-Globin Expression in Human Erythroid Cells by Directly Modulating BCL11A
Valentina Lulli et al.
PLOS ONE (2013)
Increased Levels of Antigen-Bound β-Amyloid Autoantibodies in Serum and Cerebrospinal Fluid of Alzheimer's Disease Patients
Madalina Maftei et al.
PLOS ONE (2013)
Alzheimer's Disease: Analyzing the Missing Heritability
Perry G. Ridge et al.
PLOS ONE (2013)
In Vivo Quantitative Susceptibility Mapping (QSM) in Alzheimer's Disease
Julio Acosta-Cabronero et al.
PLOS ONE (2013)
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism
Samuel I. A. Cohen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: Implications for diagnostic and therapeutic strategies
Zhichun Chen et al.
PROGRESS IN NEUROBIOLOGY (2013)
Autophagic/lysosomal dysfunction in Alzheimer's disease
Miranda E. Orr et al.
ALZHEIMERS RESEARCH & THERAPY (2013)
The role of APP and BACE1 trafficking in APP processing and amyloid-beta generation
Xiaojie Zhang et al.
ALZHEIMERS RESEARCH & THERAPY (2013)
A delicate balance: Iron metabolism and diseases of the brain
Dominic Hare et al.
FRONTIERS IN AGING NEUROSCIENCE (2013)
Iron and hepcidin: a story of recycling and balance
Clara Camaschella
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2013)
Amyloid imaging in cognitively normal individuals, at-risk populations and preclinical Alzheimer's disease
Gael Chetelat et al.
NEUROIMAGE-CLINICAL (2013)
Lipopolysaccharide induces IFN-gamma production in human NK cells
Leonid M. Kanevskiy et al.
FRONTIERS IN IMMUNOLOGY (2013)
Dysfunction of the mTOR pathway is a risk factor for Alzheimer’s disease
Sharon C Yates et al.
Acta Neuropathologica Communications (2013)
Synaptic Mitochondrial Pathology in Alzheimer's Disease
Heng Du et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Hepcidin and iron homeostasis
Tomas Ganz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Intestinal Commensal Microbes as Immune Modulators
Ivaylo I. Ivanov et al.
CELL HOST & MICROBE (2012)
AICD Nuclear Signaling and Its Possible Contribution to Alzheimer's Disease
Uwe Konietzko
CURRENT ALZHEIMER RESEARCH (2012)
Roles of Glycogen Synthase Kinase 3 in Alzheimer's Disease
Zhiyou Cai et al.
CURRENT ALZHEIMER RESEARCH (2012)
TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells
Hiroaki Ito et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Iron homeostasis in astrocytes and microglia is differentially regulated by TNF-α and TGF-β1
Khizr I. Rathore et al.
GLIA (2012)
Mitochondrial Dysfunction and Immune Activation are Detectable in Early Alzheimer's Disease Blood
Katie Lunnon et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Sustained Submicromolar H2O2 Levels Induce Hepcidin via Signal Transducer and Activator of Transcription 3 (STAT3)
Gunda Millonig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Apolipoprotein E4 Impairs Macrophage Efferocytosis and Potentiates Apoptosis by Accelerating Endoplasmic Reticulum Stress
James G. Cash et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
TLR2 Is a Primary Receptor for Alzheimer's Amyloid β Peptide To Trigger Neuroinflammatory Activation
Shirong Liu et al.
JOURNAL OF IMMUNOLOGY (2012)
Metal Binding Dictates Conformation and Function of the Amyloid Precursor Protein (APP) E2 Domain
Sven O. Dahms et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Proteolytic processing of Alzheimer's ss-amyloid precursor protein
Han Zhang et al.
JOURNAL OF NEUROCHEMISTRY (2012)
Immune profiling of Alzheimer patients
Mariavaleria Pellicano et al.
JOURNAL OF NEUROIMMUNOLOGY (2012)
Peripheral Mitochondrial Dysfunction in Alzheimer's Disease: Focus on Lymphocytes
Kristina Leuner et al.
MOLECULAR NEUROBIOLOGY (2012)
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Robert D. Bell et al.
NATURE (2012)
Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation
Joseph M. Reynolds et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Role of Natural Killer Cells in Alzheimer's Disease
F. Jadidi-Niaragh et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2012)
T cell recruitment in the brain during normal aging
Jickssa M. Gemechu et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2012)
Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease
David M. Holtzman et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)
GSK3 as a sensor determining cell fate in the brain
Adam R. Cole
FRONTIERS IN MOLECULAR NEUROSCIENCE (2012)
A pivotal role of GSK-3 in synaptic plasticity
Clarrisa A. Bradley et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2012)
Microglia function in Alzheimer's disease
Egle Solito et al.
FRONTIERS IN PHARMACOLOGY (2012)
Oxidative stress in neurodegenerative diseases
Xueping Chen et al.
NEURAL REGENERATION RESEARCH (2012)
Amyloid Precursor Protein Processing and Alzheimer's Disease
Richard J. O'Brien et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Insulin Resistance and Alzheimer-like Reductions in Regional Cerebral Glucose Metabolism for Cognitively Normal Adults With Prediabetes or Early Type 2 Diabetes
Laura D. Baker et al.
ARCHIVES OF NEUROLOGY (2011)
Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells
Thomas Weichhart et al.
BLOOD (2011)
Increased activity of Th-17 and Th-9 lymphocytes and a skewing of the post-thymic differentiation pathway are seen in Alzheimer's disease
Marina Saresella et al.
BRAIN BEHAVIOR AND IMMUNITY (2011)
Astrocytes contain amyloid-β annular protofibrils in Alzheimer's disease brains
Cristian A. Lasagna-Reeves et al.
FEBS LETTERS (2011)
Dysfunction of the Fusion of Pre-Synaptic Plasma Membranes and Synaptic Vesicles Caused by Oxidative Stress, and its Prevention by Vitamin E
Masaya Arai et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Combinatorial Markers of Mild Cognitive Impairment Conversion to Alzheimer's Disease - Cytokines and MRI Measures Together Predict Disease Progression
Simon J. Furney et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation
Beinan Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Investigation on positive correlation of increased brain iron deposition with cognitive impairment in Alzheimer disease by using quantitative MR R2' mapping
Yuanyuan Qin et al.
JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES (2011)
The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis
Jie Zhao et al.
JOURNAL OF NEUROINFLAMMATION (2011)
Oxidative stress-mediated regulation of proteasome complexes
C. T. Aiken et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
Melissa E. Murray et al.
LANCET NEUROLOGY (2011)
Proinflammatory cytokines, sickness behavior, and Alzheimer disease
C. Holmes et al.
NEUROLOGY (2011)
Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-beta toxicity
Anne Eckert et al.
ALZHEIMERS RESEARCH & THERAPY (2011)
APP processing in Alzheimer's disease
Yun-Wu Zhang et al.
MOLECULAR BRAIN (2011)
Combinatorial markers of MCI conversion: Cytokines and MRI measures together predict disease progression
Simon Lovestone et al.
Alzheimers & Dementia (2010)
Molecular interplay between mTOR, Aβ and tau: Effects on cognitive impairments
Salvatore Oddo
Alzheimers & Dementia (2010)
Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology
Paula I. Moreira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
A Meta-Analysis of Cytokines in Alzheimer's Disease
Walter Swardfager et al.
BIOLOGICAL PSYCHIATRY (2010)
Vitamin B12 Levels in Alzheimer's Disease: Association with Clinical Features and Cytokine Production
Antonis Politis et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Increased Iron and Free Radical Generation in Preclinical Alzheimer Disease and Mild Cognitive Impairment
Mark A. Smith et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
The Alzheimer's Disease Mitochondrial Cascade Hypothesis
Russell H. Swerdlow et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease
Stephen D. Ginsberg et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Reduced Posterior Cingulate Mitochondrial Activity in Expired Young Adult Carriers of the APOE epsilon 4 Allele, the Major Late-Onset Alzheimer's Susceptibility Gene
Jon Valla et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1
Hyun-Hee Cho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau EFFECTS ON COGNITIVE IMPAIRMENTS
Antonella Caccamo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Immunological Origin and Functional Properties of Catalytic Autoantibodies to Amyloid β Peptide
Sudhir Paul et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2010)
Metals, oxidative stress and neurodegenerative disorders
Klaudia Jomova et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2010)
Implications of apolipoprotein E genotype on inflammation and vitamin E status
Patricia Huebbe et al.
MOLECULAR NUTRITION & FOOD RESEARCH (2010)
Astrocytes in Alzheimer's Disease
Alexei Verkhratsky et al.
NEUROTHERAPEUTICS (2010)
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease
Marta M. Lipinski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Educating CD4 T cells with vaccine adjuvants: lessons from lipopolysaccharide
Jeremy P. McAleer et al.
TRENDS IN IMMUNOLOGY (2010)
Selective neuronal vulnerability to oxidative stress in the brain
Xinkun Wang et al.
FRONTIERS IN AGING NEUROSCIENCE (2010)
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease
Wolfgang J. Streit et al.
ACTA NEUROPATHOLOGICA (2009)
mTOR's role in ageing: protein synthesis or autophagy?
Sarah L. Hands et al.
AGING-US (2009)
Oxidative Stress and Autophagy in the Regulation of Lysosome-Dependent Neuron Death
Violetta N. Pivtoraiko et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation
Cinzia Dello Russo et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases
Catherine M. Cahill et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2009)
Astroglia in dementia and Alzheimer's disease
J. J. Rodriguez et al.
CELL DEATH AND DIFFERENTIATION (2009)
Oxidative Stress and Insulin Resistance The Coronary Artery Risk Development in Young Adults study
Kyong Park et al.
DIABETES CARE (2009)
Direct recognition of LPS by human but not murine CD8+ T cells via TLR4 complex
Mousa Komai-Koma et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2009)
Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway
Long Chen et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Dramatic Shifts in Circulating CD4 but not CD8 T Cell Subsets in Mild Alzheimer's Disease
Anis Larbi et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis
Sandro Altamura et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
mTOR signaling at a glance
Mathieu Laplante et al.
JOURNAL OF CELL SCIENCE (2009)
Lipopolysaccharide Potentiates Effector T Cell Accumulation into Nonlymphoid Tissues through TRIF
Jeremy P. McAleer et al.
JOURNAL OF IMMUNOLOGY (2009)
Oxidative stress promotes JNK-dependent amyloidogenic processing of normally expressed human APP by differential modification of α-, β- and γ-secretase expression
Ricardo Quiroz-Baez et al.
NEUROCHEMISTRY INTERNATIONAL (2009)
Systemic inflammation and disease progression in Alzheimer disease
C. Holmes et al.
NEUROLOGY (2009)
Quantitative MR Phase-corrected Imaging to Investigate Increased Brain Iron Deposition of Patients with Alzheimer Disease
Wen-zhen Zhu et al.
RADIOLOGY (2009)
Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease
Lisa Mosconi et al.
MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)
Catalytic antibodies to amyloid β peptide in defense against Alzheimer disease
Hiroaki Taguchi et al.
AUTOIMMUNITY REVIEWS (2008)
Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease
Jack T. Rogers et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Plasma antibodies to Aβ40 and Aβ42 in patients with Alzheimer's disease and normal controls
Wuhua Xu et al.
BRAIN RESEARCH (2008)
Enhanced B-cell activation mediated by TLR4 and BCR crosstalk
Susana Minguet et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses
Jason A. Hall et al.
IMMUNITY (2008)
The modulatory effects of lipopolysaccharide-stimulated B cells on differential T-cell polarization
Hui Xu et al.
IMMUNOLOGY (2008)
Hydrogen peroxide promotes Aβ production through JNK-dependent activation of γ-secretase
Chengyong Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The ubiquitin-proteasome system in Alzheimer's disease
Salvatore Oddo
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
A potential pathogenetic role of iron in Alzheimer's disease
Laura Silvestri et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2008)
Dopamine-modified α-synuclein blocks chaperone-mediated autophagy
Marta Martinez-Vicente et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Lipid peroxidation up-regulates BACE1 expression in vivo:: a possible early event of amyloidogenesis in Alzheimer's disease
Liuji Chen et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras
Scot R. Kimball et al.
JOURNAL OF PINEAL RESEARCH (2008)
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
P. Hemachandra Reddy et al.
TRENDS IN MOLECULAR MEDICINE (2008)
The GSK3 hypothesis of Alzheimer's disease
Claudie Hooper et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Oxidative stress activates a positive feedback between the γ- and β-secretase cleavages of the β-amyloid precursor protein
Elena Tamagno et al.
JOURNAL OF NEUROCHEMISTRY (2008)
mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex
John T. Cunningham et al.
NATURE (2007)
Oxidative inhibition of protein phosphatase 2A activity: Role of catalytic subunit disulfides
Timothy D. Foley et al.
NEUROCHEMICAL RESEARCH (2007)
Environmental risk factors for Parkinson's disease and parkinsonism: the Geoparkinson study
F. D. Dick et al.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2007)
Expression of APP pathway mRNAs and proteins in Alzheimer's disease
Toshifumi Matsui et al.
BRAIN RESEARCH (2007)
Damage to lipids, proteins, DNA, and RNA in mild cognitive impairment
William R. Markesbery et al.
ARCHIVES OF NEUROLOGY (2007)
Intracellular amyloid-β in Alzheimer's disease
Frank M. LaFerla et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Effects of apoE genotype on macrophage inflammation and heme oxygenase-1 expression
Laia Jofro-Monseny et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Metal ions differentially influence the aggregation and deposition of Alzheimer's β-amyloid on a solid template
Chanki Ha et al.
BIOCHEMISTRY (2007)
Variations in the APP gene promoter region and risk of Alzheimer disease
L. Guyant-Marechal et al.
NEUROLOGY (2007)
Systemic infections and inflammation affect chronic neurodegeneration
V. Hugh Perry et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Increased level of active GSK-3β in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration
K. Leroy et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2007)
Soluble protein oligomers in neurodegeneration:: lessons from the Alzheimer's amyloid β-peptide
Christian Haass et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Oxidative damage, protein synthesis, and protein degradation in Alzheimer's disease
Qunxing Ding et al.
CURRENT ALZHEIMER RESEARCH (2007)
Deferoxamine synergistically enhances iron-mediated AP-1 activation: A showcase of the interplay between extracellular-signal-regulated kinase and tyrosine phosphatase
Xi Huang et al.
FREE RADICAL RESEARCH (2007)
STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo
Antonello Pietrangelo et al.
GASTROENTEROLOGY (2007)
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
Maria Vittoria Verga Falzacappa et al.
BLOOD (2007)
GSK3α exhibits β-catenin and tau directed kinase activities that are modulated by Wnt
Ayodeji A. Asuni et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2006)
Interleukin induces hepcidin expression through STAT3
Diedra M. Wrighting et al.
BLOOD (2006)
Furin is an endogenous regulator of α-secretase associated APP processing
Eun Mi Hwang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
The role of iron regulatory proteins in mammalian iron homeostasis and disease
Tracey A. Rouault
NATURE CHEMICAL BIOLOGY (2006)
Influence of oxidative stress on fusion of pre-synaptic plasma membranes of the rat brain with phosphatidylcholine liposomes, and protective effect of vitamin E
Nao-omi Omoi et al.
JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY (2006)
Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide
Marc Mikhael et al.
FEBS JOURNAL (2006)
Apolipoprotein E4: A causative factor and therapeutic target in neuropathology including Alzheimer's disease
RW Mahley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment
HM Schipper et al.
NEUROBIOLOGY OF AGING (2006)
Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: Relevance to schizophrenia
P Steullet et al.
NEUROSCIENCE (2006)
Association between glycogen synthase kinase-3 beta genetic polymorphism and late-onset Alzheimer's disease
I Mateo et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2006)
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains
M Mishto et al.
NEUROBIOLOGY OF AGING (2006)
Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity
SJ Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mitochondrial Aβ:: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
C Caspersen et al.
FASEB JOURNAL (2005)
Astrocytes: regulation of brain homeostasis via apolipoprotein E
JR Gee et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
β-amyloid-induced neuronal apoptosis involves c-Jun N-terminal kinase-dependent downregulation of Bcl-w
MZ Yao et al.
JOURNAL OF NEUROSCIENCE (2005)
Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease
A Hye et al.
NEUROSCIENCE LETTERS (2005)
Gene structure and organization of the human β-secretase (BACE) promoter
K Sambamurti et al.
FASEB JOURNAL (2004)
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases
J Choi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
EM Blalock et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Immune response to Aβ-peptides in peripheral blood from patients with Alzheimer's disease and control subjects
L Baril et al.
NEUROSCIENCE LETTERS (2004)
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
EM Reiman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Pathways towards and away from Alzheimer's disease
MP Mattson
NATURE (2004)
Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Aβ peptides
XD Huang et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2004)
Apolipoprotein E and β-amyloid (1-42) regulation of glycogen synthase kinase-3β
A Cedazo-Mínguez et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Peroxynitrite and nitric oxide differently target the iron-sulfur cluster and amino acid residues of human iron regulatory protein 1
E Soum et al.
BIOCHEMISTRY (2003)
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
CJ Phiel et al.
NATURE (2003)
Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
LB Yang et al.
NATURE MEDICINE (2003)
Nitric oxide-mediated modulation of iron regulatory proteins: Implication for cellular iron homeostasis
S Kim et al.
BLOOD CELLS MOLECULES AND DISEASES (2002)
Apolipoprotein E deficiency promotes increased oxidative stress and compensatory increases in antioxidants in brain tissue
TB Shea et al.
FREE RADICAL BIOLOGY AND MEDICINE (2002)
Nitric oxide and peroxynitrite activate the iron regulatory protein-1 of J774A.1 macrophages by direct disassembly of the Fe-S cluster of cytoplasmic aconitase
G Cairo et al.
BIOCHEMISTRY (2002)
Atypical inflammation in the central nervous system in prion disease
VH Perry et al.
CURRENT OPINION IN NEUROLOGY (2002)
Mental deterioration correlates with response of natural killer (NK) cell activity to physiological modifiers in patients with short history of Alzheimer's disease
RG Masera et al.
PSYCHONEUROENDOCRINOLOGY (2002)
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
X Sun et al.
NEUROSCIENCE LETTERS (2002)
Roles of metallothionein in copper homeostasis: responses to Cu-deficient diets in mice
KT Suzuki et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2002)
The influence of oxidation of membrane thiol groups on lysosomal proton permeability
FY Wan et al.
BIOCHEMICAL JOURNAL (2001)
Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion
AL Bulteau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Modulation of cellular iron metabolism by hydrogen peroxide -: Effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts
A Caltagirone et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Degradation of oxidized proteins by the 20S proteasome
KJA Davies
BIOCHIMIE (2001)
Redox-active iron mediates amyloid-β toxicity
CA Rottkamp et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Lysosomal membrane damage in soluble Aβ-mediated cell death in Alzheimer's disease
K Ditaranto et al.
NEUROBIOLOGY OF DISEASE (2001)
Oxidative regulation of fatty acid-induced tau polymerization
TC Gamblin et al.
BIOCHEMISTRY (2000)
Lipopolysaccharide stimulates the proliferation of human CD56+CD3- NK cells:: A regulatory role of monocytes and IL-10
MR Goodier et al.
JOURNAL OF IMMUNOLOGY (2000)
Oxidative insults are associated with apolipoprotein E genotype in Alzheimer's disease brain
C Ramassamy et al.
NEUROBIOLOGY OF DISEASE (2000)