期刊
MOLECULAR BIOLOGY AND EVOLUTION
卷 35, 期 6, 页码 1550-1552出版社
OXFORD UNIV PRESS
DOI: 10.1093/molbev/msy073
关键词
phylogenetics; bioinformatics; missing distance imputation; rate heterogeneity over sites
资金
- Natural Science and Engineering Research Council of Canada [RGPIN-2018-03878]
DAMBE is a comprehensive software package for genomic and phylogenetic data analysis on Windows, Linux, and Macintosh computers. New functions include imputing missing distances and phylogeny simultaneously (paving the way to build large phage and transposon trees), new bootstrapping/jackknifing methods for PhyPA (phylogenetics from pairwise alignments), and an improved function for fast and accurate estimation of the shape parameter of the gamma distribution for fitting rate heterogeneity over sites. Previous method corrects multiple hits for each site independently. DAMBE's new method uses all sites simultaneously for correction. DAMBE, featuring a user-friendly graphic interface, is freely available from http://dambe.bio.uottawa.ca (last accessed, April 17, 2018).
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