期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 18, 期 13, 页码 1072-1094出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557518666180305160856
关键词
Marine-derived Aspergillus; metabolites; cytotoxic; antimicrobial; antioxidant; enzymatic activities; structure-activity
Recently, the marine-derived Aspergillus present as producers of a large number of structurally novel secondary metabolites. Some of these metabolites have shown antitumor, antimicrobial, anti-inflammatory, antioxidant and enzymatic activities, and may be promising resources for new therapeutic drugs. This review sums up 232 new bioactive metabolites from the marine-derived Aspergillus with classification through their biological activities and chemical structures in 2006-2016. Besides, structure-activity relationships of some compounds are explored.
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