期刊
MINI-REVIEWS IN MEDICINAL CHEMISTRY
卷 18, 期 9, 页码 745-775出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557517666171003103245
关键词
Biological properties; derivatives; diversity; recent progress; steroid; structure
资金
- National Key R&D Program of China [2017YFD0200502]
- Applied Basic Research Program of Wuhan City [2016020101010093]
- Hubei Agricultural Science Innovation Centre [2016-620-000-001-039]
- National Natural Science Foundation of China [31400153]
Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5 alpha-reductase inhibitors and neuromuscular blocking agents etc. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper is to review the recent advances of steroid-based derivatives mainly focused on their structures and biological applications, which can be employed for further development to discover potential drug candidates.
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