4.7 Article

Tunable composites prepared from graphene oxide and zeolitic imidazolate framework-8 for improved selective isolation of hemoglobin

期刊

MICROCHIMICA ACTA
卷 185, 期 8, 页码 -

出版社

SPRINGER WIEN
DOI: 10.1007/s00604-018-2904-5

关键词

Zeolitic imidazolate framework; Graphene oxide nanosheets; Crystal growth template and terminator; Surface morphology modulator; Hemoglobin selective separation; Human whole blood

资金

  1. National Natural Science Foundation of China [21605122, 21505104, 21545007, 21575114]
  2. Natural Science Foundation of Shaanxi Province [2018JQ2011, 2018JZ2001]
  3. Foundation of Key Laboratory in Shaanxi Province [16JS116, 15JS115]

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The authors report on the preparation of composites made from graphene oxide (GO) and zeolitic imidazolate framework-8 (ZIF-GO), with various fractions of GO. GO acts as the template and as a modulator for the surface properties of the composites. It also improves the selective adsorption of specific proteins, i.e. hemoglobin (Hb) in this case. The adsorption capacity for Hb is as high as 436 mg g(-1) when using a composite containing 20% of GO as sorbent, and 95% of specific activity is maintained for the Hb recovered. The sorbent is applied to selectively isolate Hb from human whole blood.

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