期刊
BASAL GANGLIA
卷 3, 期 3, 页码 159-163出版社
ELSEVIER
DOI: 10.1016/j.baga.2013.05.002
关键词
Parkinson's disease; Non-motor symptoms
资金
- National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre and Dementia Unit at South London
- National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre and Dementia Unit at Maudsley NHS Foundation Trust
- King's College London
Background: In Parkinson's disease (PD), visual signs and symptoms as part of sensory dysfunction are a common complaint that leads to a significant decrease in the vision related quality of life. However, they remain under-reported, under-recognized and poorly understood. In this review we wish to give a systematic overview about the published data about vision and PD. We performed a bibliographic research on an international medical literature database (PUBMED) of studies in English language published until April 2013. We specifically addressed visual symptoms and signs with retinal and ocular origin as well as their prevalence, pathophysiology and treatment. Our research indicates that PD is associated with a wide range of visual symptoms. The prevalence of all visual symptoms contains about 78%. Common complaints are a decrease in contrast insensitivity and colour discrimination as well as problems with visualspatial misperceptions, blink rate, blepharospasm, occular movements, diplopia, pain, visual field defects and visual hallucinations. The treatment is limited and the management complex. Visual problems in PD occur with varying frequency and many remain unreported and need special testing. The impact of these problems on the health-related quality of life of patients with PD is not yet well established and time has come to address these issues with further research and development for instance of a validated clinical/bedside tool for assessment of visual function in PD. (C) 2013 Elsevier GmbH. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据