期刊
出版社
ELSEVIER
DOI: 10.1016/j.msec.2017.12.011
关键词
Optimal ratio; D-Glucose; L-Aspartic acid; Carbon dots; Targeting brain cancer
资金
- Science and Technology Research Project of Jilin Province [20160101292JC]
- Research Project of Science and Technology of the Education Department of Jilin Province [2016322]
Targeting imaging to the desired site of action can increase the accuracy and effectiveness of diagnostic and treatment. In this work, a series of fluorescent carbon dots (CDs) were prepared by varying molar ratios of D-glucose (Glu) to L-aspartic acid (Asp). Their photophysical properties, morphologies and structures were investigated in detail. More important, the targeting ability was screened by confocal laser scanning microscopy and flow cytometry. The results indicate that CDs prepared from the optimal molar ratio of Glu/Asp (7:3) exhibit the highest targeting ability on C6 glioma cells, This work highlights the interplay of molecular design and corresponding functions, and open new possibility of developing state-of-art nanoparticles for biomedical applications.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据