期刊
MACROMOLECULAR BIOSCIENCE
卷 18, 期 8, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201800077
关键词
cell detection; drug delivery; nanogels; proteins and peptide enrichment; reflux precipitation polymerization
资金
- National Science Foundation of China [51633001, 21474017, 51721002, 51603042]
- State Key Project of Research and Development [2016YFC1100300]
Reflux precipitation polymerization (RPP) represents an effective approach that enables to prepare various types of polymeric nanogels with precise control over the morphology and structure. Owing to facile loading or modification by a variety of functional moieties, rationally designed nanogels pose the possibility to attain a platform for tailoring functional properties that could be widely used for various biomedical applications, such as multifunctional drug delivery, enrichment of functional peptides, separation of specific proteins, as well as detection of circulating tumor cells. This feature article highlights RPP as a promising polymerization strategy that provides access to facile generation of modular nanostructures or multifunctional properties in a diverse range of biomedical applications, proving that RPP has great potential to become one of the most attractive polymerization techniques in polymer chemistry.
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