4.7 Article

Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus

期刊

EMERGING INFECTIOUS DISEASES
卷 19, 期 10, 页码 1685-1687

出版社

CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid1910.130728

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资金

  1. National Grand Program on Key Infectious Disease Control [2012ZX10001-006, 2013ZX10001-002, 2012ZX10004-211]
  2. China Ministry of Health
  3. Ministry of Science and Technology of the People's Republic of China [2012CB519005]

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Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus based neutralization assay with preliminary assessment using subtype H7N9-infected samples and controls.

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