4.7 Article

Human Granulocytic Anaplasmosis, Japan

期刊

EMERGING INFECTIOUS DISEASES
卷 19, 期 2, 页码 289-292

出版社

CENTERS DISEASE CONTROL
DOI: 10.3201/eid1902.120855

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资金

  1. Association for Preventive Medicine of Japan
  2. Japanese Ministry of Health, Labour and Welfare [H18-Shinkou-Ippan-014, H21-Shinkou-Ippan-006, H24-Shinkou-Ippan-008]
  3. Japanese Ministry of Education, Culture, Sports, Science and Technology
  4. Grants-in-Aid for Scientific Research [23406012, 23590514] Funding Source: KAKEN

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We retrospectively confirmed 2 cases of human Anaplasma phagocytophilum infection. Patient blood samples contained unique p44/msp2 for the pathogen, and antibodies bound to A. phagocytophilum antigens propagated in THP-1 rather than HL60 cells. Unless both cell lines are used for serodiagnosis of rickettsiosis-like infections, cases of human granulocytic anaplasmosis could go undetected.

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