期刊
EMERGING INFECTIOUS DISEASES
卷 19, 期 5, 页码 802-805出版社
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid1905.121852
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资金
- Alberta Health Services
- National Institutes of Health [R21-AI085374-01A1]
- UCSD Genetics Training Program through National Institute of General Medical Sciences [T32 GM008666]
- Wellcome Trust of Great Britain
Patients with Plasmodium vivax malaria are treated with primaquine to prevent relapse infections. We report primaquine failure in a patient with 3 relapses without any possibility of re-infection. Using whole genome sequencing of the relapsing parasite isolates, we identified single nucleotide variants as candidate molecular markers of resistance.
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