Risk based 3-dimensional and multifloor plant layout optimization for liquefied natural gas (LNG) liquefaction process

This paper presents a mathematical formulation for solving a 3-dimensional and multifloor plant layout problem with safety considerations. The presented model is formulated as a mixed integer non-linear programming (MINLP) model and quantifies risk by utilizing Dow's fire and explosion index (Dow's F&EI) system. The applicability of the model is demonstrated by an illustrative example regarding layout optimization for the C3MR liquefaction processes.