期刊
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
卷 7, 期 4, 页码 3163-3169出版社
DR M N KHAN
关键词
Biodegradation; Ampicillin; Verticillium leptobactrum; White rot fungi; HPLC
资金
- Cooperative Research Program for Agriculture Science & Technology Development Rural Development Administration, Republic of Korea
The worldwide higher usage and release of Pharmaceutical and Personal Care Products (PPCPs) into is an emerging environmental issue as it has adverse effects to humans, animals, plants and microorganisms. Hence it is necessary to find a novel mechanism to degrade and remove these PPCPs from the polluted site. One of the possible methods is employing white rot fungi, as it has the capability of degrading lignin. In this study, use of white rot fungi Verticillium leptobactrum KCTC 26026 to degrade a beta-lactam antibiotic ampicillin was investigated. The antibiotic was added at a concentration of 0.5 mg L-1, 1.0 mg L-3 and 2.0 mg L-1 and incubated for 7 days in a laboratory simulated environment. The HPLC-DAD studies have shown 100% depletion of ampicillin. To the best of our knowledge, this is the first study in which white rot fungi Verticillium leptobactrum KCTC 26026 was employed for degrading antibiotic.
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