期刊
JOURNAL OF TRANSLATIONAL MEDICINE
卷 16, 期 -, 页码 -出版社
BIOMED CENTRAL LTD
DOI: 10.1186/s12967-018-1500-0
关键词
HIV; Tat; Cardiovascular diseases
资金
- National Natural Science Foundation of China [81673426]
- National Natural Science Foundation of Heilongjiang Province [LC2015034]
The human immunodeficiency virus (HIV) is a major global public health issue. HIV-related cardiovascular disease remains a leading cause of morbidity and mortality in HIV positive patients. HIV Tat is a regulatory protein encoded by tat gene of HIV-1, which not only promotes the transcription of HIV, but it is also involved in the pathogenesis of HIV-related complications. This review is aimed at summarizing the current understanding of Tat in HIV-related cardiovascular diseases.
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