期刊
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
卷 155, 期 6, 页码 2567-2574出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.jtcvs.2017.12.137
关键词
right ventricular outflow tract reconstruction; ePTFE valved conduit; bulging sinus; fan-shaped valve
资金
- W.L. Gore & Associates, Inc
Objective: Various types of conduits are available for right ventricular outflow tract (RVOT) reconstruction. We have developed an expanded polytetrafluoroethylene (ePTFE) conduit with bulging sinuses and a fan-shaped ePTFE valve. This study summarized the results of a multicenter study evaluating the valved ePTFE conduit. Methods: The valve functions of 902 patients (median age, 3.9 years; median weight, 12.6 kg) who underwent RVOT reconstruction using valved ePTFE conduits (9 different sizes, 8-24 mm in diameter) at 65 hospitals between 2001 and 2015 were retrospectively investigated. Median follow-up time was 5.5 years. The valve functions were assessed using echocardiography, cardiac catheterization, and magnetic resonance angiography. Results: There were no deaths related to the ePTFE conduit. The peak RVOT gradient was 16.5 +/- 13.1 mm Hg, and pulmonary insufficiency graded better than mild was 95.9% at the latest follow-up. Conduit replacement was performed in 55 patients, and in only 3 patients because of conduit infection. Freedom from intervention at 5 years and 10 years was 92.3% and 76.1%, respectively, with small conduits (8-16 mm in diameter) and 99.6% and 95.1%, respectively, with large conduits (18-24 mm in diameter). Conclusions: The long-term outcomes of the ePTFE conduit with a fan-shaped valve and bulging sinuses appear clinically satisfactory. We believe that the longevity of small-sized conduits can yield sufficient time to exchange them to larger-sized conduits without any loss of their valve functions. Regarding longevity and resistance to infections, this ePTFE valved conduit can be one of the best ways to reconstruct the RVOT.
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