期刊
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
卷 65, 期 9, 页码 1136-1146出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/jccs.201800157
关键词
biohybrid; cathodoluminescence; correlative light-electron microscopy; imaging; nanodiamond
资金
- Ministry of Science and Technology, Taiwan [106-2628-M-001-004]
- Academia Sinica
Cathodoluminescence (CL) and correlative light-electron microscopy (CLEM) are two useful analytical tools in diverse research areas. Recently, fluorescent nanodiamonds (FNDs) have emerged as promising imaging agents for both CL and CLEM owing to their exceptional photophysical and chemical properties. However, to realize their practical applications in the life sciences, surface modification and functionalization of the nanomaterials with bioactive molecules are critical and essential. Here we provide a comprehensive review on the methods of synthesizing biohybrid FNDs as well as recent advances of CL and CLEM imaging of cells with these carbon nanoparticles as dual-contrast markers.
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