期刊
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 140, 期 29, 页码 9074-9077出版社
AMER CHEMICAL SOC
DOI: 10.1021/jacs.8b05245
关键词
-
资金
- Eli Lilly and Company through the Lilly Research Award Program (LRAP)
- DOE [DE-FG02-05ER15690]
- NIH [1S10 OD020022]
- NSF [CHE-1048642]
A Cu-catalyzed method has been identified for aerobic oxidative dimerization of carbazoles and diarylamines to the corresponding N-N coupled bicarbazoles and tetraarylhydrazines. The reactions proceed under mild conditions (1 atm O-2, 60-80 degrees C) with a catalyst composed of CuBr.dimethylsulfide and N,N-dimethylaminopyridine. Reactions between carbazole and diarylamines show unusually selective cross-coupling, even with a 1:1 ratio of the two substrates. This behavior was found to arise from reversible formation of the tetraarylhydrazine. Formation of this species is kinetically favored, but cleavage of the N-N bond under the reaction conditions leads to selective formation of the thermodynamically favored cross-coupling product.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据