The prevalence of dyslipidemia in patients with diabetes mellitus of ayurveda Hospital

Background: Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. Early detection and treatment of dyslipidemia in type-2 diabetes mellitus can prevent risk for atherogenic cardiovascular disorder. The rationale of this study was to detect the lipid abnormality in diabetic patients. Methods: Necessary data was collected from the medical archives of 150 patients (73 female and 77 male) with diabetes mellitus registered in Department of pathology and biochemistry of a Ayurveda hospital established at Kolkata, India. Results: The mean ages of female and male subjects were 51.8 +/- 10.8 and 53.2 +/- 11.3 years respectively. The range and mean value of FBS in females were 113-342 mg/dl and 157.7 +/- 6.3 mg/dl, while the range and mean value of PPBS in females were 135-560 mg/dl and 275.5 +/- 12.3 mg/dl respectively. Results showed that range and mean value of FBS in males were 111-462 mg/dl and 160.8 +/- 7.4 mg/dl, while the range and mean value of PPBS in males were 136-598 mg/dl and 302.1 +/- 12.6 mg/dl respectively. Results of serum lipids showed that the mean values for total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) in female patients were 202.2 +/- 5.9 mg/dl, 168.3 +/- 8.2 mg/dl, 44.9 +/- 1.3 mg/dl, 123.6 +/- 5.2 mg/dl and 33.7 +/- 1.7 mg/dl respectively. The mean values for TC, TG, HDL-C, LDL-C and VLDL-C in male patients were 182.5 +/- 4.8 mg/dl, 128.1 +/- 10.8 mg/dl, 40.8 +/- 1.2 mg/dl, 105.4 +/- 4.8 mg/dl and 36.2 +/- 2.2 respectively. FBS showed significant positive correlation with PPBS, cholesterol, TG, and VLDL-C. PPBS also demonstrated direct and significant correlations with TG and VLDL-C. Conclusions: The study showed common lipid abnormalities during diabetes induced dyslipidemia i.e., hypercholesterolemia, hypertriglyceridemia and elevated LDL-C. This study suggests the dominance of hyperlipidemia over increased prevalence of dyslipidemia.