Feasibility of a lifestyle intervention for overweight/obese endometrial and breast cancer survivors using an interactive mobile application

Objective. The study aimed to assess a one-month lifestyle intervention delivered via a web- and mobile-based weight-loss application (app) (Loselt!) using a healthcare-provider interface. Methods. Early-stage overweight/obese (body mass index [BMI] >= 25 kg/m(2)) cancer survivors (CS) diagnosed in the past three years, and without recurrent disease were enrolled and received exercise and nutrition counseling using the Loselt! app. Entry and exit quality of life (FACT-G) and Weight Efficacy Lifestyle Quetionnaire (WEL) measuring self-efficacy were measured along with anthropometrics, daily food intake, and physical activity (PA) using the app. Results. Mean participant age was 58.4 +/- 10.3 years (n = 50). Significant reductions (p < 0.0006) in anthropometrics were noted between pre- and post-intervention weight (105.0 +/- 21.8 kg versus 98.6 +/- 22.5 kg); BMI (34.9 +/- 8.7 kg/m(2) versus 33.9 +/- 8.4 kg/m(2)); and waist circumference (108.1 +/- 14.9 cm versus 103.7 +/- 15.1 cm). A significant improvement in pre- and post-intervention total WEL score was noted (99.38 +/- 41.8 versus 120.19 +/- 47.1, p = 0.043). No significant differences were noted in FACT-G, macronutrient consumption, and PA patterns. Conclusion. These results indicate that a lifestyle intervention delivered via a web- and mobile-based weight-loss app is a feasible option by which to elicit short-term reductions in weight. Though these results parallel the recent survivors of uterine cancer empowered by exercise and healthy diet (SUCCEED) trial, it is notable that they were achieved without encumbering significant cost and barrier-access issues (i.e. time, transportation, weather, parking, etc.). (C) 2014 Published by Elsevier Inc.