4.5 Article

Compressing a confined DNA: from nano-channel to nano-cavity

期刊

JOURNAL OF PHYSICS-CONDENSED MATTER
卷 30, 期 24, 页码 -

出版社

IOP PUBLISHING LTD
DOI: 10.1088/1361-648X/aac286

关键词

DNA; confinement; compression; nanochannel

资金

  1. KAKENHI from MEXT, Japan [JP16H00804]
  2. JST, PRESTO [JPMJPR16N5]

向作者/读者索取更多资源

We analyze the behavior of a semiflexible polymer confined in nanochannel under compression in axial direction. Key to our discussion is the identification of two length scales; the correlation length. of concentration fluctuation and what we call the segregation length xi(w). These length scales, while degenerate in uncompressed state in nanochannel, generally split as xi < xi(w) upon compression, and the way they compete with the system size during the compression determines the crossover from quasi-1D nanochannel to quasi-0D nanocavity behaviors. For a flexible polymer, the story becomes very simple, which corresponds to a special limit of our description, but a much richer behavior is expected for a semiflexible polymer relevant to DNA in confined spaces. We also briefly discuss the dynamical properties of the compressed polymer.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.5
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据